{"id":25947,"date":"2022-12-15T16:05:32","date_gmt":"2022-12-15T19:05:32","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/review-paper-vs-research-paper-copy\/"},"modified":"2022-12-21T16:11:05","modified_gmt":"2022-12-21T19:11:05","slug":"stiff-person-syndrome","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/hu\/stiff-person-szindroma\/","title":{"rendered":"Merev szem\u00e9ly szindr\u00f3ma: T\u00fcnetek, okok \u00e9s kezel\u00e9s"},"content":{"rendered":"<p>Nap mint nap az izmainkra t\u00e1maszkodunk, hogy megtartsuk a k\u00e1v\u00e9nkat, dolgozzunk a laptopunkon, \u00e9s s\u00e9t\u00e1ljunk el a helyekre. De, b\u00e1r ez nem gyakori, ugyanezek az izmok n\u00e9ha cserben hagynak minket.<\/p>\n\n\n\n<p>Mindezeket a feladatokat vesz\u00e9lyezteti az autoimmunit\u00e1s \u00e9s a neurol\u00f3giai betegs\u00e9gek. Olvasson tov\u00e1bb, hogy t\u00f6bbet megtudjon err\u0151l a rendk\u00edv\u00fcl ritka rendelleness\u00e9gr\u0151l.<\/p>\n\n\n\n<h2>Mi a merev szem\u00e9ly szindr\u00f3ma?<\/h2>\n\n\n\n<p>A Stiff-person-szindr\u00f3ma, m\u00e1s n\u00e9ven Moersch-Woltman-szindr\u00f3ma egy ritka neurol\u00f3giai rendelleness\u00e9g, amely autoimmun jellegzetess\u00e9gekkel rendelkezik - k\u00f6z\u00f6lte a National Institute of Neurological Disorders and Stroke.&nbsp;<\/p>\n\n\n\n<p>Az \u00e1llapot miatt a test merevv\u00e9 v\u00e1lik, \u00e9s \u00e9rz\u00e9kenyebb\u00e9 v\u00e1lik a hangokra, az \u00e9rint\u00e9sre \u00e9s az \u00e9rzelmi zavarokra. Az int\u00e9zm\u00e9ny szerint ez a fokozott \u00e9rz\u00e9kenys\u00e9g a g\u00f6rnyedt \u00e9s fesz\u00fclt testtart\u00e1s mellett izomg\u00f6rcs\u00f6ket is eredm\u00e9nyezhet.<\/p>\n\n\n\n<p>A Stiff Person Syndrome Research Foundation szerint az izomg\u00f6rcs\u00f6k olyan er\u0151sek lehetnek, hogy elmozd\u00edthatj\u00e1k az \u00edz\u00fcleteket, \u00e9s ak\u00e1r csontokat is t\u00f6rhetnek.<\/p>\n\n\n\n<p><strong>Csak egy vagy k\u00e9t ember egymilli\u00f3b\u00f3l<\/strong> szenvednek a merev szem\u00e9ly szindr\u00f3m\u00e1ban a John Hopkins Medicine szerint. A merev szem\u00e9ly szindr\u00f3ma k\u00e9tszer annyi n\u0151t \u00e9rint, mint f\u00e9rfit. A t\u00fcnetek b\u00e1rmely \u00e9letkorban jelentkezhetnek, b\u00e1r a leggyakoribbak 30 \u00e9s 60 \u00e9ves kor k\u00f6z\u00f6tt.<\/p>\n\n\n\n<h2>A merev szem\u00e9ly szindr\u00f3ma t\u00fcnetei \u00e9s okai<\/h2>\n\n\n\n<h3>T\u00fcnetek<\/h3>\n\n\n\n<p>A szindr\u00f3ma legjelent\u0151sebb szempontja, amit hangs\u00falyozni kell, az, hogy mennyire szokatlan, \u00e9s hogy a k\u00fcl\u00f6nb\u00f6z\u0151 egy\u00e9nek hogyan reag\u00e1lnak r\u00e1; nagyon gyakori, hogy egyes betegek \u00e9vekig stabilak maradnak, m\u00edg m\u00e1sok gyorsan romlanak.<\/p>\n\n\n\n<p>A legt\u00f6bb betegn\u00e9l a t\u00f6rzs \u00e9s a hasizmok merevednek meg \u00e9s t\u00e1gulnak ki el\u0151sz\u00f6r. Ezt k\u00f6vet\u0151en \u00e1ltal\u00e1ban a k\u00f6vetkez\u0151 t\u00fcnetek jelentkeznek:&nbsp;<\/p>\n\n\n\n<ul>\n<li>F\u00e1jdalom;<\/li>\n\n\n\n<li>Izommerevs\u00e9g j\u00f6n \u00e9s megy;<\/li>\n\n\n\n<li>F\u00e1jdalmas kellemetlens\u00e9g;<\/li>\n\n\n\n<li>A l\u00e1bizmok id\u0151vel megmerevednek, ahogyan m\u00e1s izmok is az eg\u00e9sz testben;<\/li>\n\n\n\n<li>G\u00f6rnyedt testtart\u00e1s;<\/li>\n\n\n\n<li>Neh\u00e9z j\u00e1rni vagy mozogni a merevs\u00e9g miatt;<\/li>\n\n\n\n<li>Hossz\u00fa izomg\u00f6rcs\u00f6k, amelyek m\u00e1sodpercekig, percekig vagy \u00f3r\u00e1kig tarthatnak.&nbsp;<\/li>\n<\/ul>\n\n\n\n<h3>Okok<\/h3>\n\n\n\n<p>B\u00e1r a merev szem\u00e9ly szindr\u00f3ma ok\u00e1t nem azonos\u00edtott\u00e1k, a kutat\u00f3k szerint autoimmun betegs\u00e9gr\u0151l van sz\u00f3, amely az immunrendszert az eg\u00e9szs\u00e9ges sejtek elpuszt\u00edt\u00e1s\u00e1ra k\u00e9szteti. Az ebben az \u00e1llapotban szenved\u0151 egy\u00e9nek olyan antitesteket termelnek, amelyek megt\u00e1madj\u00e1k a glutaminsavdekarboxil\u00e1z enzimet (GAD).<\/p>\n\n\n\n<p>Ez az enzim elengedhetetlen a gamma-aminovajsav (GABA), az izomkoordin\u00e1ci\u00f3t seg\u00edt\u0151 neurotranszmitter el\u0151\u00e1ll\u00edt\u00e1s\u00e1hoz. A GAD c\u00e9lzottan t\u00f6rt\u00e9n\u0151 kezel\u00e9s\u00e9vel a szervezet cs\u00f6kkenti a GABA mennyis\u00e9g\u00e9t.<\/p>\n\n\n\n<p>A GAD funkci\u00f3ja a merev szem\u00e9ly szindr\u00f3ma kialakul\u00e1s\u00e1ban \u00e9s progresszi\u00f3j\u00e1ban m\u00e9g nem teljesen ismert. A val\u00f3s\u00e1gban egyes, ebben az \u00e1llapotban szenved\u0151 egy\u00e9nekn\u00e9l nem mutathat\u00f3k ki GAD-antitestek.<\/p>\n\n\n\n<p>Egy m\u00e1sik fontos t\u00e9nyez\u0151, amely hozz\u00e1j\u00e1rulhat a betegs\u00e9g kialakul\u00e1s\u00e1hoz, az a t\u00e9ny, hogy az amfifizin nev\u0171 feh\u00e9rje kev\u00e9sb\u00e9 gyakori a merev szem\u00e9ly szindr\u00f3m\u00e1ban szenved\u0151kn\u00e9l. Ez a feh\u00e9rje elengedhetetlen az idegsejtek egym\u00e1s k\u00f6z\u00f6tti k\u00f6lcs\u00f6nhat\u00e1s\u00e1hoz, \u00e9s az idegv\u00e9gz\u0151d\u00e9sekben tal\u00e1lhat\u00f3.<\/p>\n\n\n\n<h2>Hogyan diagnosztiz\u00e1lj\u00e1k \u00e9s kezelik a Stiff Person szindr\u00f3m\u00e1t?<\/h2>\n\n\n\n<h3>Diagn\u00f3zis<\/h3>\n\n\n\n<p>A merev szem\u00e9ly szindr\u00f3ma t\u00fcnetei hasonl\u00f3ak m\u00e1s betegs\u00e9gek, p\u00e9ld\u00e1ul a tetanusz, a szkler\u00f3zis multiplex \u00e9s az izomdisztr\u00f3fi\u00e1k t\u00fcneteihez. Gyakran \u00f6sszet\u00e9vesztik m\u00e1s autoimmun betegs\u00e9gekkel, p\u00e9ld\u00e1ul Parkinson-k\u00f3rral vagy szorong\u00e1s-f\u00f3bia kombin\u00e1ci\u00f3val.<\/p>\n\n\n\n<p>Az eg\u00e9szs\u00e9g\u00fcgyi szakember sz\u00e1mos vizsg\u00e1latot v\u00e9gezhet, hogy kiz\u00e1rja ezeket a rendelleness\u00e9geket, \u00e9s ellen\u0151rizze a merev szem\u00e9ly szindr\u00f3ma bizony\u00edt\u00e9kait, p\u00e9ld\u00e1ul:<\/p>\n\n\n\n<ul>\n<li><strong>V\u00e9rvizsg\u00e1lat:<\/strong> a GAC vagy az amfiphysin elleni antitestek jelenl\u00e9t\u00e9nek, valamint m\u00e1s t\u00fcneteknek a vizsg\u00e1lat\u00e1ra, amelyek m\u00e1s rendelleness\u00e9gekre utalhatnak vagy kiz\u00e1rhatj\u00e1k azokat.&nbsp;<\/li>\n\n\n\n<li><strong>Lumb\u00e1lpunkci\u00f3: <\/strong>Olyan elj\u00e1r\u00e1s, amely t\u0171 seg\u00edts\u00e9g\u00e9vel folyad\u00e9kot vesz ki a gerinccsatorn\u00e1b\u00f3l a GAC vagy az amphiphysin elleni antitestek jelenl\u00e9t\u00e9nek, valamint m\u00e1s t\u00fcneteknek a vizsg\u00e1lat\u00e1ra, amelyek m\u00e1s rendelleness\u00e9gekre utalhatnak vagy kiz\u00e1rhatj\u00e1k azokat.&nbsp;<\/li>\n\n\n\n<li><strong>Elektromiogr\u00e1fia (EMG): <\/strong>Egy g\u00e9p az izmok elektromos aktivit\u00e1s\u00e1nak m\u00e9r\u00e9s\u00e9vel \u00e9rz\u00e9keli az izmok folyamatban l\u00e9v\u0151 motoros tev\u00e9kenys\u00e9g\u00e9t.<\/li>\n<\/ul>\n\n\n\n<h2>Kezel\u00e9s<\/h2>\n\n\n\n<p>A merev szem\u00e9ly szindr\u00f3ma kezel\u00e9s\u00e9r\u0151l a t\u00fcnetek alapj\u00e1n d\u00f6ntenek, azzal a c\u00e9llal, hogy a t\u00fcnetek enyh\u00fcljenek, mik\u00f6zben javul az \u00e9letmin\u0151s\u00e9g, p\u00e9ld\u00e1ul a mobilit\u00e1s \u00e9s a k\u00e9nyelem.<\/p>\n\n\n\n<p>A kezel\u00e9s mag\u00e1ban foglalhatja:<\/p>\n\n\n\n<ul>\n<li>Benzodiazepinek, mint a diazep\u00e1m \u00e9s a klonazep\u00e1m vagy a baclofen, az izommerevs\u00e9g kezel\u00e9s\u00e9re;&nbsp;<\/li>\n\n\n\n<li>&nbsp;G\u00f6rcsold\u00f3 gy\u00f3gyszerek, gyullad\u00e1scs\u00f6kkent\u0151k \u00e9s kortikoszteroidok f\u00e1jdalomcsillap\u00edt\u00e1sra;<\/li>\n\n\n\n<li>Fizikoter\u00e1pia;<\/li>\n\n\n\n<li>Massz\u00e1zsok;<\/li>\n\n\n\n<li>V\u00edzter\u00e1pia;<\/li>\n\n\n\n<li>H\u0151ter\u00e1pia;<\/li>\n\n\n\n<li>Akupunkt\u00fara.<\/li>\n<\/ul>\n\n\n\n<p>Az intrav\u00e9n\u00e1s immunglobulin (IVIG), a plazmaferezis, a rituximab \u00e9s az autol\u00f3g \u0151ssejt-transzplant\u00e1ci\u00f3 tov\u00e1bbi kezel\u00e9si lehet\u0151s\u00e9gek, azonban ezek kev\u00e9sb\u00e9 gyakoriak.<\/p>\n\n\n\n<h2>Az adatok k\u00f6nnyen \u00e9rthet\u0151, dinamikus t\u00f6rt\u00e9netekk\u00e9 alak\u00edt\u00e1sa<\/h2>\n\n\n\n<p>Nagyon fontos, hogy a k\u00f6z\u00f6ns\u00e9g teljesen meg\u00e9rtse, mir\u0151l besz\u00e9l, amikor fontos r\u00e9szleteket k\u00f6z\u00f6l a munk\u00e1j\u00e1ban. Tudta, hogy a sz\u00ednes vizualiz\u00e1ci\u00f3k 80%-vel jav\u00edtj\u00e1k az emberek hajland\u00f3s\u00e1g\u00e1t arra, hogy elolvassanak egy sz\u00f6veget? (Forr\u00e1s: Saurage Research) Haszn\u00e1lja ki a <a href=\"https:\/\/mindthegraph.com\" target=\"_blank\" rel=\"noreferrer noopener\">Mind The Graph<\/a> eszk\u00f6zzel, \u00e9s v\u00e1lassza ki a munk\u00e1j\u00e1t legjobban le\u00edr\u00f3 sablont!<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"600\" height=\"338\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/10\/r3qiu0qenda-3.gif\" alt=\"\" class=\"wp-image-25130\"\/><\/figure><\/div>\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons\">\n<div class=\"wp-block-button aligncenter\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/\" style=\"border-radius:50px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\">Tegy\u00fck k\u00f6zz\u00e9 a kutat\u00e1sait<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:44px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>Ebb\u0151l a cikkb\u0151l megtudhatsz mindent, amit a Stiff Person Syndrome-r\u00f3l, egy nem mindennapi autoimmun betegs\u00e9gr\u0151l tudni kell. <\/p>","protected":false},"author":28,"featured_media":25956,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[959,28],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Stiff Person Syndrome: Symptoms, Causes, and Treatment<\/title>\n<meta name=\"description\" content=\"This article will teach you all you need to know about Stiff 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Currently developing scientific and intellectual knowledge for the community's benefit. Jessica is an animal rights activist who enjoys reading and drinking strong coffee.","sameAs":["https:\/\/www.linkedin.com\/in\/jessica-abbadia-9b834a13b\/"],"url":"https:\/\/mindthegraph.com\/blog\/hu\/author\/jessica\/"}]}},"_links":{"self":[{"href":"https:\/\/mindthegraph.com\/blog\/hu\/wp-json\/wp\/v2\/posts\/25947"}],"collection":[{"href":"https:\/\/mindthegraph.com\/blog\/hu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mindthegraph.com\/blog\/hu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/hu\/wp-json\/wp\/v2\/users\/28"}],"replies":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/hu\/wp-json\/wp\/v2\/comments?post=25947"}],"version-history":[{"count":4,"href":"https:\/\/mindthegraph.com\/blog\/hu\/wp-json\/wp\/v2\/posts\/25947\/revisions"}],"predecessor-version":[{"id":25963,"href":"https:\/\/mindthegraph.com\/blog\/hu\/wp-json\/wp\/v2\/posts\/25947\/revisions\/25963"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/hu\/wp-json\/wp\/v2\/media\/25956"}],"wp:attachment":[{"href":"https:\/\/mindthegraph.com\/blog\/hu\/wp-json\/wp\/v2\/media?parent=25947"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/hu\/wp-json\/wp\/v2\/categories?post=25947"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/hu\/wp-json\/wp\/v2\/tags?post=25947"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}