{"id":16662,"date":"2022-09-22T19:23:00","date_gmt":"2022-09-22T22:23:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16662"},"modified":"2023-03-17T14:46:01","modified_gmt":"2023-03-17T17:46:01","slug":"success-case-nmda-receptor-adjusted-co-administration-of-ecstasy-and-cannabinoid-receptor-1-agonist","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/hu\/success-case-nmda-receptor-szabalyozott-co-adagolas-az-ecstasy-es-kannabinoid-receptor-1-agonista-kezelesevel\/","title":{"rendered":"Az NMDA receptorhoz igaz\u00edtott ecstasy \u00e9s a kannabinoid receptor-1 agonista egy\u00fcttes alkalmaz\u00e1sa az amygdala-ban a BDNF\/Trk-B \/ CREB \u00fatvonal stimul\u00e1l\u00e1s\u00e1n kereszt\u00fcl feln\u0151tt h\u00edm patk\u00e1nyokban Paper Review"},"content":{"rendered":"<p>A grafikus \u00f6sszefoglal\u00f3k egyre n\u00e9pszer\u0171bbek a tud\u00f3sok k\u00f6r\u00e9ben. Vagyis a szerz\u0151 egy csod\u00e1latos diz\u00e1jnt hozott l\u00e9tre, hogy pontos k\u00e9pekkel magyar\u00e1zza el a cikk teljes l\u00e9nyeg\u00e9t.<\/p>\n\n\n\n<p>Ellen\u0151rizze a teljes <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0361923016303756\" target=\"_blank\" rel=\"noreferrer noopener\">eredeti cikk<\/a>.<\/p>\n\n\n\n<h2><strong>A szelekt\u00edv CB-1 agonista, p\u00e9ld\u00e1ul az ACPA fogyaszt\u00e1sa megv\u00e9di az idegsejteket az MDMA toxicit\u00e1ssal szemben az amygdala-ban<\/strong><\/h2>\n\n\n\n<p>Az \"NMDA receptor \u00e1ltal be\u00e1ll\u00edtott ecstasy \u00e9s kannabinoid receptor-1 agonista egy\u00fcttes alkalmaz\u00e1sa az amygdala-ban a BDNF \/ Trk-B \/ CREB \u00fatvonal stimul\u00e1l\u00e1s\u00e1n kereszt\u00fcl feln\u0151tt h\u00edm patk\u00e1nyokban\" Ashabi \u00e9s munkat\u00e1rsai (2017) megjegyezt\u00e9k, hogy az NMDA blokkol\u00e1s cs\u00f6kkentette a neuron\u00e1lis t\u00fczel\u00e9si sebess\u00e9get \u00e9s a tirozin-kin\u00e1z B \/ agyi neurotr\u00f3pikus faktor \/ CAMP v\u00e1laszelem k\u00f6t\u0151 feh\u00e9rje szintj\u00e9t MDMA \u00e9s CB1 receptor agonista egy\u00fcttes bead\u00e1s\u00e1val beadott patk\u00e1nyokban. <\/p>\n\n\n\n<p>A glutamatergikus rendszer a TrK-B receptorokon kereszt\u00fcl szab\u00e1lyozza az MDMA \u00e9s az ACPA kombin\u00e1ci\u00f3 v\u00e9d\u0151 szerep\u00e9t.<\/p>\n\n\n\n<h2><strong>Grafikus \u00f6sszefoglal\u00f3k az Mind the Graph seg\u00edts\u00e9g\u00e9vel<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"835\" height=\"305\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png\" alt=\"\" class=\"wp-image-20094\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png 835w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-300x110.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-768x281.png 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-18x7.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-100x37.png 100w\" sizes=\"(max-width: 835px) 100vw, 835px\" \/><figcaption class=\"wp-element-caption\"><em>K\u00e9sz\u00fclt&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<p>A CB1-receptor aktiv\u00e1l\u00e1sa vagy az MDMA indukci\u00f3ja cs\u00f6kkentette a neuronok t\u00fczel\u00e9si sebess\u00e9g\u00e9t. E k\u00e9t gy\u00f3gyszer egyidej\u0171 injekci\u00f3z\u00e1sa fokozta a neuronsejtek t\u00fal\u00e9l\u00e9s\u00e9t, \u00e9s ezeket az esem\u00e9nyeket NMDA-receptor-antagonista seg\u00edts\u00e9g\u00e9vel visszaford\u00edtott\u00e1k. <\/p>\n\n\n\n<p>Val\u00f3sz\u00edn\u0171leg a glutam\u00e1terg receptorok v\u00e9d\u0151 szerepe a BDNF\/Trk-B \u00fatvonalak aktiv\u00e1l\u00e1s\u00e1n kereszt\u00fcl val\u00f3sulhat meg. <\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"718\" height=\"512\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png\" alt=\"\" class=\"wp-image-20093\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png 718w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-300x214.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-18x12.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-100x71.png 100w\" sizes=\"(max-width: 718px) 100vw, 718px\" \/><figcaption class=\"wp-element-caption\"><em>K\u00e9sz\u00fclt&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<h2><strong>Pap\u00edrok hat\u00e1sa \u00e9s teljes\u00edtm\u00e9nye<\/strong><\/h2>\n\n\n\n<p>Ha a metrik\u00e1k 1 \u00e9ves \u00f6sszehasonl\u00edt\u00e1s\u00e1t v\u00e1lasztjuk m\u00e1s olyan cikkekkel\/\u00e9rt\u00e9kel\u00e9sekkel, amelyeket ugyanabban a napt\u00e1ri \u00e9vben szint\u00e9n az adott foly\u00f3iratban tettek k\u00f6zz\u00e9, akkor meg\u00e1llap\u00edthatjuk, hogy <strong>ezt a cikket t\u00f6bbsz\u00f6r id\u00e9zt\u00e9k, mint 47% k\u00f6z\u00fcl\u00fck<\/strong>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"377\" height=\"330\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png\" alt=\"\" class=\"wp-image-20096\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png 377w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-300x263.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-14x12.png 14w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-100x88.png 100w\" sizes=\"(max-width: 377px) 100vw, 377px\" \/><\/figure>\n\n\n\n<p>Haszn\u00e1lja ki az infografik\u00e1k erej\u00e9t a cikkei fellend\u00edt\u00e9s\u00e9re is. Pr\u00f3b\u00e1lja ki az Mind the Graph-t!<\/p>","protected":false},"excerpt":{"rendered":"<p>Tanuljon azokt\u00f3l, akik m\u00e1r felfedezt\u00e9k az infografik\u00e1k erej\u00e9t. Ez a cikk az Mind the Graph seg\u00edts\u00e9g\u00e9vel k\u00e9sz\u00fclt grafikai kivonatokat tartalmazza. <\/p>","protected":false},"author":29,"featured_media":20081,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NMDA receptor adjusted co-administration of ecstasy and cannabinoid receptor-1 agonist in the amygdala via stimulation of BDNF\/Trk-B\/CREB pathway in adult male rats Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Learn with the ones who already discovered the power of infographics. 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