{"id":16657,"date":"2022-09-14T13:04:15","date_gmt":"2022-09-14T16:04:15","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16657"},"modified":"2023-03-17T14:47:26","modified_gmt":"2023-03-17T17:47:26","slug":"success-case-xtalkdb-a-database-of-signaling-pathway-crosstalk","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/hu\/success-case-xtalkdb-a-database-of-signaling-pathway-crosstalk\/","title":{"rendered":"XTALKDB: a jel\u00e1tviteli \u00fatvonalak keresztbesz\u00e9lget\u00e9s\u00e9nek adatb\u00e1zisa Paper Review"},"content":{"rendered":"

Ez a csod\u00e1latos cikk az XTALKDB-ben tal\u00e1lhat\u00f3 adatokat \u00f6sszefoglal\u00f3 statisztik\u00e1kat mutatja be. A szerz\u0151 n\u00e9h\u00e1ny perc alatt k\u00e9sz\u00edtett egy infografik\u00e1t, amely az XTALKDB-ben szerepl\u0151 fajok eloszl\u00e1s\u00e1t magyar\u00e1zza el.<\/p>\n\n\n\n

Ellen\u0151rizze a eredeti cikk itt<\/a>.<\/p>\n\n\n\n

Mivel az emberek vizu\u00e1lis l\u00e9nyek, a k\u00e9pek m\u00e9g mindig a legjobb m\u00f3dja annak, hogy olyan r\u00e9szletess\u00e9ggel magyar\u00e1zza el a kutat\u00e1s\u00e1t, amennyire csak akarja.<\/p>\n\n\n\n

A tud\u00f3sok kifejlesztettek egy adatb\u00e1zist, amely dokument\u00e1lja a jel\u00e1tviteli \u00fatvonalak specifikus p\u00e1rjai, valamint a fajok \u00e9s sz\u00f6vetek k\u00f6z\u00f6tti keresztkapcsolatokat, amelyekben megfigyelhet\u0151ek.<\/strong><\/h2>\n\n\n\n

A Biol\u00f3giai Tudom\u00e1nyok Tansz\u00e9k Sarah Sam \u00e1ltal vezetett kutat\u00f3csoport (2016) arr\u00f3l sz\u00e1molt be, hogy a receptorok \u00e1ltal \u00e9rz\u00e9kelt k\u00fcls\u0151 jel hat\u00e1s\u00e1ra a k\u00f6ztes feh\u00e9rj\u00e9k aktivit\u00e1sa megv\u00e1ltozik. <\/p>\n\n\n\n

Ez a transzkripci\u00f3s faktorok szab\u00e1lyoz\u00e1s\u00e1t eredm\u00e9nyezi, amelyek m\u00f3dos\u00edtj\u00e1k a c\u00e9lg\u00e9nek kifejez\u0151d\u00e9s\u00e9t. Az XTalkDB minden egyes \u00fatvonalp\u00e1rhoz r\u00e9szletes inform\u00e1ci\u00f3kat r\u00f6gz\u00edt, amelyek le\u00edrj\u00e1k azokat a k\u00eds\u00e9rleti felt\u00e9teleket, amelyek mellett a keresztbesz\u00e9lget\u00e9st felfedezt\u00e9k. <\/p>\n\n\n\n

A sejtek jel\u00e1tviteli \u00fatvonalakon kereszt\u00fcl \u00e9rt\u00e9kelik k\u00f6rnyezet\u00fcket \u00e9s reag\u00e1lnak r\u00e1. Egy jel\u00e1tviteli \u00fatvonal jellemz\u0151en a receptorok, k\u00f6ztes jel\u00e1tviteli feh\u00e9rj\u00e9k, transzkripci\u00f3s faktorok \u00e9s c\u00e9lg\u00e9nek k\u00f6z\u00f6tti szab\u00e1lyoz\u00e1si \u00e9s fizikai k\u00f6lcs\u00f6nhat\u00e1sok j\u00f3l meghat\u00e1rozott csoportj\u00e1t tartalmazza. <\/p>\n\n\n\n

Az XTalkDB weboldal egy k\u00f6nnyen haszn\u00e1lhat\u00f3 fel\u00fcletet biztos\u00edt a tud\u00f3sok sz\u00e1m\u00e1ra, hogy egy vagy t\u00f6bb \u00fatvonal vagy molekula lek\u00e9rdez\u00e9s\u00e9vel b\u00f6ng\u00e9szhess\u00e9k a keresztbesz\u00e9lget\u00e9sre vonatkoz\u00f3 inform\u00e1ci\u00f3kat.<\/p>\n\n\n\n

A vizsg\u00e1latban 650 p\u00e1r vett r\u00e9szt.<\/strong><\/p>\n\n\n\n

Grafikus absztrakt az Mind the Graph seg\u00edts\u00e9g\u00e9vel<\/strong><\/h2>\n\n\n
\n
\"success-case-XTALKDB-a-database-of-signaling-pathway-crosstalk\"<\/a>
K\u00e9sz\u00fclt Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

A lehets\u00e9ges fejleszt\u00e9sekr\u0151l sz\u00f3lva: \"Az XTalkDB alapj\u00e1ul szolg\u00e1l\u00f3 k\u00e9zi kur\u00e1tori folyamatnak megvannak a maga korl\u00e1tai, k\u00fcl\u00f6n\u00f6sen, ha az adatb\u00e1zis lefedetts\u00e9g\u00e9t szeretn\u00e9nk b\u0151v\u00edteni. <\/p>\n\n\n\n

Tervezz\u00fck egy olyan term\u00e9szetes nyelvi feldolgoz\u00e1si keretrendszer kifejleszt\u00e9s\u00e9t, amely a publik\u00e1ci\u00f3kat aszerint \u00e9rt\u00e9keli, hogy milyen val\u00f3sz\u00edn\u0171s\u00e9ggel dokument\u00e1lj\u00e1k a keresztbesz\u00e9lget\u00e9st. A kur\u00e1tor ezut\u00e1n a magasan rangsorolt publik\u00e1ci\u00f3kra \u00f6sszpontos\u00edthat\" - vallj\u00e1k.<\/p>\n\n\n\n

Pap\u00edrok hat\u00e1sa \u00e9s teljes\u00edtm\u00e9nye<\/strong><\/h2>\n\n\n\n

Elemezhetj\u00fck a Altmetric<\/a> adatok, hogy ez a pap\u00edr a az \u00f6sszes metrika fels\u0151 r\u00e9sze az NIH \u00e1ltal a Dimenzi\u00f3kban finansz\u00edrozott \u00f6sszes cikken bel\u00fcl. <\/strong><\/p>\n\n\n

\n
\"\"<\/a>
Forr\u00e1s: https:\/\/badge.dimensions.ai\/details\/id\/pub.1052462103<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Haszn\u00e1lja ki az infografik\u00e1k erej\u00e9t a cikkei fellend\u00edt\u00e9s\u00e9re is. Pr\u00f3b\u00e1lja ki az Mind the Graph-t!<\/p>\n\n\n\n

<\/div>\n\n\n\n
\n
Pr\u00f3b\u00e1lja ki az Mind the Graph-t<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

Tanuljon azokt\u00f3l, akik m\u00e1r felfedezt\u00e9k az infografik\u00e1k erej\u00e9t. Ez a cikk az Mind the Graph seg\u00edts\u00e9g\u00e9vel k\u00e9sz\u00fclt grafikai kivonatokat tartalmazza. <\/p>","protected":false},"author":29,"featured_media":20046,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"\nXTALKDB: a database of signaling pathway crosstalk Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"This amazing article brings out statistics summarizing data in XTALKDB with an infographic explaining the distribution of the species in XTALKDB.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/hu\/success-case-xtalkdb-a-database-of-signaling-pathway-crosstalk\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"XTALKDB: a database of signaling pathway crosstalk Paper Review - 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