{"id":16651,"date":"2022-09-12T18:50:00","date_gmt":"2022-09-12T21:50:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16651"},"modified":"2023-03-17T14:47:35","modified_gmt":"2023-03-17T17:47:35","slug":"success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/hu\/success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties\/","title":{"rendered":"A krotoxin immunter\u00e1pi\u00e1s potenci\u00e1lja: gyullad\u00e1scs\u00f6kkent\u0151 \u00e9s immunszuppressz\u00edv tulajdons\u00e1gok Paper Review"},"content":{"rendered":"<p>A krotoxin gyullad\u00e1scs\u00f6kkent\u0151 modul\u00e1ci\u00f3j\u00e1t a megfelel\u0151 k\u00e9pek n\u00e9lk\u00fcl kiss\u00e9 neh\u00e9z lenne elmagyar\u00e1zni, de ez\u00e9rt l\u00e9tezik az Mind the Graph!<\/p>\n\n\n\n<h2><strong>A cs\u00f6rg\u0151k\u00edgy\u00f3 m\u00e9rg\u00e9vel, a krotoxinnal kapcsolatos tudom\u00e1nyos kutat\u00e1sok \u00e1ttekint\u00e9se<\/strong><\/h2>\n\n\n\n<p>Marco Sartim \u00e9s munkat\u00e1rsai (2018) \"Immunotherapeutic potential of Crotoxin\" c\u00edm\u0171 tanulm\u00e1nyukban megjegyezt\u00e9k, hogy az elm\u00falt 80 \u00e9vben a k\u00edgy\u00f3m\u00e9regb\u0151l izol\u00e1lt toxinok k\u00f6z\u00fcl a krotoxin lett az egyik legt\u00f6bbet vizsg\u00e1lt izol\u00e1lt toxin. <\/p>\n\n\n\n<p>A krotoxin a d\u00e9l-amerikai cs\u00f6rg\u0151k\u00edgy\u00f3 Crotalus durissus terrificus m\u00e9rg\u00e9nek f\u0151 m\u00e9rgez\u0151 \u00f6sszetev\u0151je. Vizsg\u00e1latok kimutatt\u00e1k, hogy a C.d.t. immunmodul\u00e1l\u00f3 hat\u00e1sa gyullad\u00e1sg\u00e1tl\u00f3 medi\u00e1torok termel\u00e9s\u00e9vel f\u00fcgg \u00f6ssze. <\/p>\n\n\n\n<p>A krotoxin \u00e9s alegys\u00e9geinek immunrendszert modul\u00e1l\u00f3 k\u00e9pess\u00e9ge \u00faj t\u00e1vlatokat nyitott a potenci\u00e1lis ter\u00e1pi\u00e1s szerek sz\u00e1m\u00e1ra.<\/p>\n\n\n\n<p><strong>A kutat\u00f3k 161 cikket vizsg\u00e1ltak meg.<\/strong><\/p>\n\n\n\n<p>Ellen\u0151rizze a <a href=\"https:\/\/jvat.biomedcentral.com\/articles\/10.1186\/s40409-018-0178-3\" target=\"_blank\" rel=\"noreferrer noopener\">eredeti cikk itt<\/a>.<\/p>\n\n\n\n<h2><strong>Grafikus \u00f6sszefoglal\u00f3k az Mind the Graph seg\u00edts\u00e9g\u00e9vel<\/strong><\/h2>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"1003\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp\" alt=\"\" class=\"wp-image-20251\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp 1024w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-300x294.webp 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-768x752.webp 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-12x12.webp 12w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-100x98.webp 100w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp 1418w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>K\u00e9sz\u00fclt <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>A szerz\u0151 az Mind the Graph platformot haszn\u00e1lta fel a Crotoxin \u00e9s alegys\u00e9gei \u00e1ltal a gyullad\u00e1sos stimulus sor\u00e1n modul\u00e1lt kering\u00e9si, sz\u00f6veti \u00e9s sejtszint\u0171 esem\u00e9nyek sematikus \u00e1br\u00e1j\u00e1nak l\u00e9trehoz\u00e1s\u00e1ra.<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML.webp\"><img decoding=\"async\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML-839x1024.webp\" alt=\"\" class=\"wp-image-20252\"\/><\/a><figcaption class=\"wp-element-caption\"><em>K\u00e9sz\u00fclt <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>A szerz\u0151 r\u00e9szletesen bemutatta a v\u00e9rkering\u00e9st, a limfocit\u00e1k nyirokcsom\u00f3ba t\u00f6rt\u00e9n\u0151 hazat\u00e9r\u00e9s\u00e9t, valamint a Crotoxin \u00e9s alegys\u00e9geinek immunszuppressz\u00edv hat\u00e1s\u00e1val kapcsolatos sejtes esem\u00e9nyeket is.<\/p>\n\n\n\n<p><strong>Ez az infografik\u00e1k ereje!<\/strong><\/p>\n\n\n\n<p>A szerz\u0151k k\u00f6vetkeztet\u00e9sei meger\u0151s\u00edteni l\u00e1tszanak az e ter\u00fcleten v\u00e9gzett kor\u00e1bbi munk\u00e1kat: \"A krotoxin k\u00e9pes volt elnyomni a HAS-immuniz\u00e1lt egerek specifikus anti-HSA IgG1 \u00e9s IgG2a antitest termel\u00e9s\u00e9t, ami azt jelzi, hogy k\u00e9pes modul\u00e1lni a Th1 \u00e9s Th2 v\u00e1laszokat\" - \u00e1ll\u00edtotta Sartim.<\/p>\n\n\n\n<h2><strong>Pap\u00edrok hat\u00e1sa \u00e9s teljes\u00edtm\u00e9nye<\/strong><\/h2>\n\n\n\n<p>Elemezhetj\u00fck a <a href=\"https:\/\/mindthegraph.com\/blog\/altmetric\/\" target=\"_blank\" rel=\"noreferrer noopener\">Altmetric<\/a> hogy ez a tanulm\u00e1ny t\u00f6bb id\u00e9z\u00e9st kapott <strong>mint a <strong>84%<\/strong><\/strong> <strong>a Springer Nature m\u00e1s cikkei.<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\"><img decoding=\"async\" loading=\"lazy\" width=\"322\" height=\"578\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\" alt=\"\" class=\"wp-image-20254\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png 322w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-167x300.png 167w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-7x12.png 7w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-56x100.png 56w\" sizes=\"(max-width: 322px) 100vw, 322px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Forr\u00e1s <a href=\"https:\/\/citations.springernature.com\/item?doi=10.1186\/s40409-018-0178-3&amp;start=11&amp;years=&amp;journals=&amp;books=&amp;authors=\" target=\"_blank\" rel=\"noreferrer noopener\">Crossref<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Haszn\u00e1lja ki az infografik\u00e1k erej\u00e9t, hogy fellend\u00edtse \u00e9s <a href=\"https:\/\/mindthegraph.com\/blog\/research-journal-impact-factor\/\">befoly\u00e1solja a cikket<\/a> is. Pr\u00f3b\u00e1lja ki az Mind the Graph-t!<\/p>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/app\/auth\/register?from_url=\/\" style=\"border-radius:100px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Pr\u00f3b\u00e1lja ki az Mind the Graph-t<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:46px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>","protected":false},"excerpt":{"rendered":"<p>A krotoxin gyullad\u00e1scs\u00f6kkent\u0151 modul\u00e1ci\u00f3j\u00e1t megfelel\u0151 k\u00e9pek n\u00e9lk\u00fcl kiss\u00e9 neh\u00e9z lehet megmagyar\u00e1zni, de az Mind the Graph l\u00e9tezik!<\/p>","protected":false},"author":29,"featured_media":20047,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - 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