{"id":16424,"date":"2022-08-17T19:00:25","date_gmt":"2022-08-17T22:00:25","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16424"},"modified":"2022-10-18T08:23:41","modified_gmt":"2022-10-18T11:23:41","slug":"what-is-a-fecal-transplant","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/hu\/mi-az-a-szeklet-transzplantacio\/","title":{"rendered":"Sz\u00e9klet\u00e1t\u00fcltet\u00e9s: Mi ez, hogyan m\u0171k\u00f6dik \u00e9s milyen mell\u00e9khat\u00e1sai vannak?"},"content":{"rendered":"<p>A kutat\u00e1sok egyre nagyobb teret h\u00f3d\u00edtanak a hum\u00e1n b\u00e9lmikrobiom szab\u00e1lyoz\u00e1s\u00e1val kapcsolatos ter\u00e1pi\u00e1s el\u0151ny\u00f6k jobb meg\u00e9rt\u00e9se \u00e9rdek\u00e9ben. Az FMT, a sz\u00e9klet\u00e1t\u00fcltet\u00e9s, a bakterioter\u00e1pia \u00e9s a b\u00e9lmikrobi\u00f3ta-transzplant\u00e1ci\u00f3 is a sz\u00e9klet\u00e1t\u00fcltet\u00e9s kifejez\u00e9sek k\u00f6z\u00e9 tartozik. Az orvosok sz\u00e9klet\u00e1t\u00fcltet\u00e9seket v\u00e9geznek, hogy eg\u00e9szs\u00e9ges donorokt\u00f3l sz\u00e1rmaz\u00f3 sz\u00e9klet \u00e1t\u00fcltet\u00e9s\u00e9vel p\u00f3tolj\u00e1k a bakt\u00e9riumok term\u00e9szetes egyens\u00faly\u00e1t az ember b\u00e9lrendszer\u00e9ben. M\u00e1s betegs\u00e9gek, p\u00e9ld\u00e1ul gyomor-b\u00e9lrendszeri fert\u0151z\u00e9sek is kezelhet\u0151k sz\u00e9klet\u00e1t\u00fcltet\u00e9ssel.<\/p>\n\n\n\n<p>Egyes betegs\u00e9gek \u00e9s antibiotikumok elpuszt\u00edthatj\u00e1k az em\u00e9szt\u0151rendszerben l\u00e9v\u0151 hasznos bakt\u00e9riumokat, megakad\u00e1lyozva a t\u00e1panyagok felsz\u00edv\u00f3d\u00e1s\u00e1t. A j\u00f3 bakt\u00e9riumok vissza\u00e1ll\u00edt\u00e1sa sz\u00e9klet\u00e1t\u00fcltet\u00e9ssel \u00e9rhet\u0151 el.<\/p>\n\n\n\n<p>A sz\u00e9klet-mikrobi\u00f3ta transzplant\u00e1ci\u00f3 (FMT) c\u00e9lja a recipiens b\u00e9lmikrobiomj\u00e1nak megv\u00e1ltoztat\u00e1sa a donorb\u00f3l sz\u00e1rmaz\u00f3 sz\u00e9klet oldat\u00e1nak a recipiens b\u00e9lrendszer\u00e9be t\u00f6rt\u00e9n\u0151 bead\u00e1s\u00e1val. A Clostridium difficile fert\u0151z\u00e9s ki\u00fajul\u00e1s\u00e1t sikeresen kezelt\u00e9k FMT-vel. Ahogy folytatjuk az olvas\u00e1st, t\u00f6bbet fogunk megtudni a sz\u00e9kletsz\u00e1ll\u00edt\u00e1sr\u00f3l.<\/p>\n\n\n\n<h2><strong><strong>Mi a sz\u00e9klet\u00e1t\u00fcltet\u00e9s menete?<\/strong><\/strong><\/h2>\n\n\n\n<p>Ge Hong a negyedik sz\u00e1zadi K\u00edn\u00e1ban le\u00edrta, hogy a sz\u00e9kletet hasmen\u00e9s kezel\u00e9s\u00e9re haszn\u00e1lt\u00e1k, \u00e9s ez volt az els\u0151 alkalom, hogy a sz\u00e9kletet ter\u00e1pi\u00e1s c\u00e9lokra haszn\u00e1lt\u00e1k. A transzplant\u00e1ci\u00f3 bead\u00e1s\u00e1nak m\u00f3dja alapj\u00e1n k\u00fcl\u00f6nb\u00f6z\u0151 FMT-elj\u00e1r\u00e1sok l\u00e9teznek. A vastagb\u00e9lt\u00fckr\u00f6z\u00e9s r\u00e9szek\u00e9nt a gasztroenterol\u00f3gus a transzplant\u00e1ci\u00f3 bead\u00e1sa el\u0151tt s\u00f3s vizes oldatot kever \u00f6ssze a donor sz\u00e9klet\u00e9b\u0151l vett mint\u00e1val. A sz\u00e9klet\u00e1t\u00fcltet\u00e9snek nincs szil\u00e1rd \u00f6sszetev\u0151je. Az orvosoknak \u00e1t kell vizsg\u00e1lniuk a potenci\u00e1lis donorokat:<\/p>\n\n\n\n<ul class=\"has-white-color has-text-color has-background\" style=\"background-color:#dc1866\"><li>V\u00edrusok, mint p\u00e9ld\u00e1ul a hepatitis A, B \u00e9s C<\/li><\/ul>\n\n\n\n<ul class=\"has-white-color has-text-color has-background\" style=\"background-color:#dc1866\"><li>HIV\/AIDS<\/li><\/ul>\n\n\n\n<ul class=\"has-white-color has-text-color has-background\" style=\"background-color:#dc1866\"><li>Szifilisz<\/li><\/ul>\n\n\n\n<ul class=\"has-white-color has-text-color has-background\" style=\"background-color:#dc1866\"><li>B\u00e9lparazit\u00e1k, p\u00e9ld\u00e1ul giardiasis vagy f\u00e9rgek okozta fert\u0151z\u00e9sek.<\/li><\/ul>\n\n\n\n<ul class=\"has-white-color has-text-color has-background\" style=\"background-color:#dc1866\"><li>C. difficile<\/li><\/ul>\n\n\n\n<ul class=\"has-white-color has-text-color has-background\" style=\"background-color:#dc1866\"><li>Az orvos \u00e1ltal javasolt egy\u00e9b felt\u00e9telek<\/li><\/ul>\n\n\n\n<p>Az \u00e1t\u00fcltet\u00e9s befejez\u00e9se ut\u00e1n nyugtat\u00f3 gy\u00f3gyszert adnak \u00d6nnek, \u00e9s a vastagb\u00e9lt\u00fckr\u00f6z\u00e9shez megfelel\u0151 testhelyzetben az oldal\u00e1ra fektetik. A v\u00e9gb\u00e9len kereszt\u00fcl egy kamer\u00e1val ell\u00e1tott endoszk\u00f3pot vagy kolonoszk\u00f3pot vezetnek be a vastagb\u00e9lbe egy hajl\u00e9kony cs\u0151vel egy\u00fctt. A sz\u00e9klet\u00e1t\u00fcltet\u00e9s sor\u00e1n egy permetezett folyad\u00e9kot permeteznek a vastagb\u00e9l fal\u00e1ra, mik\u00f6zben az orvos visszah\u00fazza a t\u00e1vcs\u00f6vet.<\/p>\n\n\n\n<p>A hasmen\u00e9s megel\u0151z\u00e9s\u00e9t seg\u00edt\u0151 gy\u00f3gyszereket \u00edrhatnak fel a t\u00e1voz\u00e1s el\u0151tt, hogy seg\u00edtsenek fenntartani a sz\u00e9klet\u00e1t\u00fcltet\u00e9st a vastagb\u00e9lben. A beavatkoz\u00e1s ut\u00e1n hazamehet, vagy a nap h\u00e1tral\u00e9v\u0151 r\u00e9sz\u00e9t a k\u00f3rh\u00e1zi szob\u00e1j\u00e1ban t\u00f6ltheti.<\/p>\n\n\n\n<h2><strong>Kinek van sz\u00fcks\u00e9ge erre az elj\u00e1r\u00e1sra?<\/strong><\/h2>\n\n\n\n<p>A s\u00falyos bakteri\u00e1lis fert\u0151z\u00e9sek, mint p\u00e9ld\u00e1ul a C. difficile kezel\u00e9se sz\u00e9klet\u00e1t\u00fcltet\u00e9ssel t\u00f6rt\u00e9nik.  A C. diffile kezel\u00e9s\u00e9ben \u00e1ltal\u00e1ban antibiotikumokat alkalmaznak, mint a legt\u00f6bb fert\u0151z\u00e9s eset\u00e9ben. Alkalmank\u00e9nt azonban a fert\u0151z\u00e9s egyes emberekn\u00e9l visszat\u00e9rhet. Az antibiotikumok szapor\u00edt\u00e1s\u00e1ra nem lesz v\u00e1laszreakci\u00f3.<\/p>\n\n\n\n<p>A visszat\u00e9r\u0151 C. diff-et sikeresebben kezelik sz\u00e9klet\u00e1t\u00fcltet\u00e9ssel, mint antibiotikumokkal. A fert\u0151z\u00e9sek \u00e1ltal\u00e1ban r\u00f6vid id\u0151n bel\u00fcl megsz\u0171nnek ezt a kezel\u00e9st k\u00f6vet\u0151en.<\/p>\n\n\n\n<p>Bizony\u00edt\u00e9kok arra utalnak, hogy m\u00e1s betegs\u00e9gek, p\u00e9ld\u00e1ul gyullad\u00e1sos b\u00e9lbetegs\u00e9gek, elh\u00edz\u00e1s, metabolikus szindr\u00f3ma \u00e9s funkcion\u00e1lis gasztrointesztin\u00e1lis betegs\u00e9gek eset\u00e9n is el\u0151ny\u00f6s lehet.<\/p>\n\n\n\n<h2><strong><strong>Id\u0151f\u00fcgg\u0151 mell\u00e9khat\u00e1sok<\/strong><\/strong><\/h2>\n\n\n\n<p>A transzplant\u00e1tum bead\u00e1s\u00e1nak m\u00f3dja \u00e1ltal\u00e1ban a mell\u00e9khat\u00e1sok oka. A sz\u00e9klet\u00e1t\u00fcltet\u00e9s leggyakoribb m\u00f3dja (vastagb\u00e9lt\u00fckr\u00f6z\u00e9s) olyan \u00e1tmeneti mell\u00e9khat\u00e1sokat eredm\u00e9nyezhet, mint p\u00e9ld\u00e1ul:<\/p>\n\n\n\n<ul class=\"has-black-color has-cyan-bluish-gray-background-color has-text-color has-background\"><li>Gasztritisz \u00e9s puffad\u00e1s<\/li><li>Ki\u00fct\u00e9s \u00e9s h\u00e1nyinger<\/li><li>Az elj\u00e1r\u00e1s sor\u00e1n egy l\u00e9gzseb g\u00f6rcs\u00f6ket okozhat a vastagb\u00e9lben.<\/li><li>Hasmen\u00e9ssel \u00f6sszef\u00fcgg\u0151 sz\u00e9kreked\u00e9s<\/li><li>A v\u00e9gb\u00e9lny\u00edl\u00e1sb\u00f3l n\u00e9h\u00e1ny csepp transzplant\u00e1ci\u00f3s oldat sziv\u00e1rog.<\/li><\/ul>\n\n\n\n<p>A k\u00e1ros mell\u00e9khat\u00e1sok lehet\u0151s\u00e9ge ritka, de l\u00e9tezik. N\u00e9h\u00e1ny p\u00e9lda:<\/p>\n\n\n\n<ul class=\"has-black-color has-cyan-bluish-gray-background-color has-text-color has-background\"><li>Azok a donorok, akiket nem vizsg\u00e1lnak meg \u00e9s nem tesztelnek gondosan, m\u00e1s bakt\u00e9riummal vagy v\u00edrussal fert\u0151z\u0151dhetnek meg.<\/li><li>A beteg t\u00fcd\u0151gyullad\u00e1st kap a nasogastricus cs\u0151vel vagy orrcs\u0151vel v\u00e9gzett FMT sor\u00e1n.<\/li><li>A kolonoszk\u00f3pia vagy endoszk\u00f3pia tipikus kock\u00e1zatai k\u00f6z\u00e9 tartozik a fert\u0151z\u00e9s, a v\u00e9rz\u00e9s, a perfor\u00e1ci\u00f3, a szakad\u00e1s \u00e9s az altat\u00e1s kock\u00e1zata.<\/li><\/ul>\n\n\n\n<p>A kutat\u00e1sok sor\u00e1n azonban azt tal\u00e1lt\u00e1k, hogy ezek a hat\u00e1sok gyakran nem k\u00e1rosak, \u00e9s \u00e1ltal\u00e1ban id\u0151vel megsz\u0171nnek.<\/p>\n\n\n\n<h2><strong><strong>Sz\u00e9klet\u00e1t\u00fcltet\u00e9s el\u0151k\u00e9sz\u00edt\u00e9se<\/strong><\/strong><\/h2>\n\n\n\n<ul class=\"has-white-color has-text-color has-background\" style=\"background-color:#dc1866\"><li>Minden gy\u00f3gyszert \u00e9s allergi\u00e1t k\u00f6z\u00f6lnie kell orvos\u00e1val.<\/li><\/ul>\n\n\n\n<ul class=\"has-white-color has-text-color has-background\" style=\"background-color:#dc1866\"><li>Az el\u0151k\u00e9sz\u00edt\u00e9si utas\u00edt\u00e1sokat kezel\u0151orvosa a beavatkoz\u00e1s el\u0151tt megbesz\u00e9li \u00d6nnel. Nagyon fontos, hogy szorosan k\u00f6vesse az ir\u00e1nymutat\u00e1sokat.<\/li><\/ul>\n\n\n\n<ul class=\"has-white-color has-text-color has-background\" style=\"background-color:#dc1866\"><li>A beavatkoz\u00e1s el\u0151tt k\u00e9t nappal minden antibiotikumot abba kell hagynia.<\/li><\/ul>\n\n\n\n<ul class=\"has-white-color has-text-color has-background\" style=\"background-color:#dc1866\"><li>A v\u00e9nyk\u00f6teles gy\u00f3gyszerek mellett k\u00e9rdezze meg orvos\u00e1t a v\u00e9ny n\u00e9lk\u00fcl kaphat\u00f3 gy\u00f3gyszerekr\u0151l, term\u00e9szetes gy\u00f3gym\u00f3dokr\u00f3l \u00e9s t\u00e1pl\u00e1l\u00e9kkieg\u00e9sz\u00edt\u0151kr\u0151l is. Kezel\u0151orvosa seg\u00edteni fogja \u00d6nt a transzplant\u00e1ci\u00f3ra val\u00f3 felk\u00e9sz\u00fcl\u00e9sben azzal, hogy elmagyar\u00e1zza \u00d6nnek, mikor \u00e9s hogyan kell szednie ezeket a gy\u00f3gyszereket.<\/li><\/ul>\n\n\n\n<ul class=\"has-white-color has-text-color has-background\" style=\"background-color:#dc1866\"><li>Ha a transzplant\u00e1ci\u00f3t kolonoszk\u00f3pi\u00e1val v\u00e9gzik, akkor a kolonoszk\u00f3pi\u00e1hoz sz\u00fcks\u00e9ges b\u00e9lel\u0151k\u00e9sz\u00edt\u00e9si rendet kell k\u00f6vetni. A beavatkoz\u00e1s el\u0151tt orvosa utas\u00edthatja \u00d6nt, hogy tiszta folyad\u00e9kot fogyasszon \u00e9s hashajt\u00f3t haszn\u00e1ljon.<\/li><\/ul>\n\n\n\n<ul class=\"has-white-color has-text-color has-background\" style=\"background-color:#dc1866\"><li>Nyugtat\u00f3 gy\u00f3gyszert kell alkalmazni, ha az FMT endoszk\u00f3pia vagy kolonoszk\u00f3pia \u00fatj\u00e1n t\u00f6rt\u00e9nik.&nbsp;<\/li><\/ul>\n\n\n\n<p>Tal\u00e1n furcs\u00e1nak t\u0171nhet, hogy egy eg\u00e9szs\u00e9ges donort\u00f3l fogadjuk el a sz\u00e9kletet, de a sz\u00e9klet\u00e1t\u00fcltet\u00e9s a tudom\u00e1nynak k\u00f6sz\u00f6nhet\u0151en egyre ink\u00e1bb elterjedt.<\/p>\n\n\n\n<p>A b\u00e9lrendszer eg\u00e9szs\u00e9g\u00e9t er\u0151s\u00edt\u0151 hat\u00e9kony kezel\u00e9s ide\u00e1lis megold\u00e1s lehet, ha m\u00e1s kezel\u00e9sek nem m\u0171k\u00f6dnek, mivel serkenti a hasznos bakt\u00e9riumok szaporod\u00e1s\u00e1t, er\u0151s\u00edti az immunrendszer m\u0171k\u00f6d\u00e9s\u00e9t, \u00e9s hozz\u00e1j\u00e1rul az egy\u00e9n j\u00f3l\u00e9t\u00e9hez. A sz\u00e9klet\u00e1t\u00fcltet\u00e9st orvosok \u00e1ltal\u00e1ban nem v\u00e9gzik, ez\u00e9rt olyan szak\u00e9rt\u0151 tan\u00e1cs\u00e1t kell k\u00e9rnie, aki kell\u0151 szak\u00e9rtelemmel rendelkezik ezen a ter\u00fcleten.<\/p>\n\n\n\n<h2><strong>Gy\u0151z\u0151dj\u00f6n meg r\u00f3la, hogy a tudom\u00e1nyos illusztr\u00e1ci\u00f3 a hely\u00e9n van<\/strong><\/h2>\n\n\n\n<p>A Mind the graph seg\u00edts\u00e9g\u00e9vel b\u00e1rmilyen kutat\u00e1st vizu\u00e1lisan szeml\u00e9ltethet, \u00e9s sz\u00e9les k\u00f6z\u00f6ns\u00e9get \u00e9rhet el munk\u00e1j\u00e1val. Hogy seg\u00edts\u00fcnk projektjeidben, k\u00f6nyvt\u00e1runkban nagy illusztr\u00e1ci\u00f3s gy\u0171jtem\u00e9ny \u00e1ll rendelkez\u00e9sedre. Emellett szak\u00e9rt\u0151i csapatunkat is felk\u00e9rheti, hogy az \u00d6n ig\u00e9nyei szerint testre szabja. Tov\u00e1bbi inform\u00e1ci\u00f3k\u00e9rt k\u00e9rj\u00fck, l\u00e1togasson el <a href=\"https:\/\/mindthegraph.com\/\">weboldal<\/a>.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Tutorial | Tudom\u00e1nyos poszter k\u00e9sz\u00edt\u00e9se\" width=\"800\" height=\"450\" src=\"https:\/\/www.youtube.com\/embed\/NdSYKg-QyII?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>Itt az ideje, hogy megtudja, mi a sz\u00e9klet\u00e1t\u00fcltet\u00e9s, kinek van r\u00e1 sz\u00fcks\u00e9ge, milyen mell\u00e9khat\u00e1sai vannak, \u00e9s mindent megtudjon az elj\u00e1r\u00e1ssal kapcsolatban.<\/p>","protected":false},"author":27,"featured_media":16428,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[959,28,956],"tags":[913,554,775,914],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Fecal Transplant: Understand what it is, how it works and the side effects<\/title>\n<meta name=\"description\" content=\"It&#039;s time to learn what Fecal Transplant is, who needs it, the side effects and everything about the procedure.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/hu\/czym-jest-przeszczep-kalu\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta 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