{"id":16670,"date":"2022-09-16T19:40:00","date_gmt":"2022-09-16T22:40:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16670"},"modified":"2023-03-17T14:47:16","modified_gmt":"2023-03-17T17:47:16","slug":"success-case-nuclear-receptors-in-liver-fibrosis","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/fr\/success-case-nuclear-receptors-in-liver-fibrosis\/","title":{"rendered":"Les r\u00e9cepteurs nucl\u00e9aires dans la fibrose du foie : revue de presse"},"content":{"rendered":"

Dans ce cas, l'auteur a utilis\u00e9 Mind the Graph pour compiler des chiffres provenant de diff\u00e9rentes sources en un seul endroit. Outre des illustrations d'une grande pr\u00e9cision scientifique, notre espace de travail poss\u00e8de une interface conviviale et est tr\u00e8s facile \u00e0 utiliser.<\/p>\n\n\n\n

V\u00e9rifiez l'int\u00e9gralit\u00e9 article original<\/a>. <\/p>\n\n\n\n

R\u00f4le des r\u00e9cepteurs nucl\u00e9aires dans la fibrose du foie<\/strong><\/h2>\n\n\n\n

Philipp K\u00f6nigshofer et al. (2021) rapportent que les r\u00e9cepteurs nucl\u00e9aires sont des facteurs de transcription activ\u00e9s par des ligands qui r\u00e9gulent l'expression g\u00e9n\u00e9tique d'une vari\u00e9t\u00e9 de signaux mol\u00e9culaires cl\u00e9s impliqu\u00e9s dans la fibrose du foie. <\/p>\n\n\n\n

Le principal moteur cellulaire de la fibrogen\u00e8se du foie est l'activation des cellules stellaires h\u00e9patiques. Diff\u00e9rents r\u00e9cepteurs nucl\u00e9aires r\u00e9gulent l'expression h\u00e9patique des cytokines pro-inflammatoires et pro-fibrog\u00e8nes.<\/p>\n\n\n\n

R\u00e9sum\u00e9s graphiques propuls\u00e9s par Mind the Graph<\/strong> dans cet article<\/strong><\/h2>\n\n\n\n
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Fabriqu\u00e9 avec Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n
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Cette premi\u00e8re figure est un aper\u00e7u et une classification des r\u00e9cepteurs nucl\u00e9aires par sous-familles.<\/p>\n\n\n\n

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Fabriqu\u00e9 avec Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

On peut voir ci-dessus les diff\u00e9rents types de fonctions effectrices des r\u00e9cepteurs nucl\u00e9aires.<\/p>\n\n\n\n

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Fabriqu\u00e9 avec Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Dans la troisi\u00e8me figure, nous pouvons v\u00e9rifier une vue d'ensemble des effets rapport\u00e9s des modulations de NR comme approches th\u00e9rapeutiques potentielles contre les maladies du foie. <\/p>\n\n\n\n

Les fl\u00e8ches indiquent les effets b\u00e9n\u00e9fiques pr\u00e9sum\u00e9s dans les maladies du foie en up- (vert fonc\u00e9)<\/strong><\/span> ou vers le bas - (vert clair)<\/span><\/strong> la r\u00e9gulation de m\u00e9canismes sp\u00e9cifiques qui ont \u00e9t\u00e9 signal\u00e9s pour favoriser la r\u00e9gression de la fibrose h\u00e9patique ou pour r\u00e9duire la fibrose h\u00e9patique. <\/p>\n\n\n\n

Fl\u00e8ches orange<\/mark><\/strong> indiquent des effets et des m\u00e9canismes de modulation des RN qui sont soit controvers\u00e9s, soit encore insuffisamment \u00e9valu\u00e9s.<\/p>\n\n\n\n

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Fabriqu\u00e9 avec Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

La derni\u00e8re figure repr\u00e9sente les effets mol\u00e9culaires des modulateurs de NR en tant que traitement potentiel de la fibrose h\u00e9patique, qui sont principalement signal\u00e9s comme se produisant dans les CSH.<\/p>\n\n\n\n

K\u00f6nigshofer et ses coll\u00e8gues proposent que des recherches suppl\u00e9mentaires sur la signalisation li\u00e9e aux r\u00e9cepteurs nucl\u00e9aires puissent conduire au d\u00e9veloppement clinique de th\u00e9rapies anti-fibrotiques efficaces pour les patients atteints de maladies du foie.<\/p>\n\n\n\n

Impact et performance des documents<\/strong><\/h2>\n\n\n\n

En choisissant une option de comparaison sur un an des param\u00e8tres par rapport \u00e0 d'autres articles\/r\u00e9visions qui ont \u00e9galement \u00e9t\u00e9 publi\u00e9s au cours de la m\u00eame ann\u00e9e civile dans ce journal, nous pouvons constater que cet article a \u00e9t\u00e9 plus cit\u00e9 que 57% d'entre eux<\/strong>.<\/p>\n\n\n

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Source : PlumX<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Utilisez le pouvoir des infographies pour booster votre article \u00e9galement. Essayez Mind the Graph !<\/p>\n\n\n\n

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Essayez Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

Cet article comporte des illustrations scientifiques r\u00e9alis\u00e9es avec Mind the Graph pour repr\u00e9senter les r\u00e9cepteurs nucl\u00e9aires dans la fibrose du foie.<\/p>","protected":false},"author":29,"featured_media":20044,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,775,963],"yoast_head":"\nNuclear receptors in liver fibrosis Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"This article has scientific illustrations made with Mind the Graph to represent nuclear receptors in liver fibrosis.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/fr\/success-case-nuclear-receptors-in-liver-fibrosis\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nuclear receptors in liver fibrosis Paper Review - Mind the Graph Blog\" \/>\n<meta property=\"og:description\" content=\"This article has scientific illustrations made with Mind the Graph to represent nuclear receptors in liver fibrosis.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/fr\/success-case-nuclear-receptors-in-liver-fibrosis\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2022-09-16T22:40:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-17T17:47:16+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_7.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1125\" \/>\n\t<meta property=\"og:image:height\" content=\"614\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Artur Zignani\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_7.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Artur Zignani\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Nuclear receptors in liver fibrosis Paper Review - 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