{"id":16651,"date":"2022-09-12T18:50:00","date_gmt":"2022-09-12T21:50:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16651"},"modified":"2023-03-17T14:47:35","modified_gmt":"2023-03-17T17:47:35","slug":"success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/fr\/success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties\/","title":{"rendered":"Potentiel immunoth\u00e9rapeutique de la crotoxine : propri\u00e9t\u00e9s anti-inflammatoires et immunosuppressives Paper Review"},"content":{"rendered":"<p>Il pourrait \u00eatre un peu difficile d'expliquer la modulation anti-inflammatoire de la crotoxine sans les images appropri\u00e9es, mais c'est pourquoi Mind the Graph existe !<\/p>\n\n\n\n<h2><strong>Une revue de la recherche scientifique sur la crotoxine, un venin de crotale<\/strong><\/h2>\n\n\n\n<p>Dans \" Immunotherapeutic potential of Crotoxin \", Marco Sartim et al. (2018) notent que depuis 80 ans, la Crotoxine est devenue l'une des toxines isol\u00e9es des venins de serpents les plus \u00e9tudi\u00e9es. <\/p>\n\n\n\n<p>La crotoxine est le principal composant toxique du venin du crotale sud-am\u00e9ricain Crotalus durissus terrificus. Des \u00e9tudes ont montr\u00e9 que l'effet immunomodulateur du C.d.t. est associ\u00e9 \u00e0 la production de m\u00e9diateurs anti-inflammatoires. <\/p>\n\n\n\n<p>La capacit\u00e9 de la crotoxine et de ses sous-unit\u00e9s \u00e0 moduler le syst\u00e8me immunitaire a ouvert de nouvelles perspectives en tant qu'agents th\u00e9rapeutiques potentiels.<\/p>\n\n\n\n<p><strong>Les chercheurs ont examin\u00e9 161 articles.<\/strong><\/p>\n\n\n\n<p>V\u00e9rifiez le <a href=\"https:\/\/jvat.biomedcentral.com\/articles\/10.1186\/s40409-018-0178-3\" target=\"_blank\" rel=\"noreferrer noopener\">article original ici<\/a>.<\/p>\n\n\n\n<h2><strong>R\u00e9sum\u00e9s graphiques propuls\u00e9s par Mind the Graph<\/strong><\/h2>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"1003\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp\" alt=\"\" class=\"wp-image-20251\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp 1024w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-300x294.webp 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-768x752.webp 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-12x12.webp 12w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-100x98.webp 100w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp 1418w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Fabriqu\u00e9 avec <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>L'auteur a utilis\u00e9 la plateforme Mind the Graph pour cr\u00e9er une figure sch\u00e9matique sur la circulation, les \u00e9v\u00e9nements tissulaires et cellulaires modul\u00e9s par la Crotoxine et ses sous-unit\u00e9s pendant le stimulus inflammatoire.<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML.webp\"><img decoding=\"async\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML-839x1024.webp\" alt=\"\" class=\"wp-image-20252\"\/><\/a><figcaption class=\"wp-element-caption\"><em>Fabriqu\u00e9 avec <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>L'auteur a \u00e9galement d\u00e9taill\u00e9 la circulation sanguine, la localisation des lymphocytes dans les ganglions lymphatiques et les \u00e9v\u00e9nements cellulaires associ\u00e9s aux effets immunosuppresseurs de la Crotoxine et de ses sous-unit\u00e9s.<\/p>\n\n\n\n<p><strong>C'est le pouvoir des infographies !<\/strong><\/p>\n\n\n\n<p>Les conclusions des auteurs semblent consolider les travaux ant\u00e9rieurs dans ce domaine : \"La crotoxine a \u00e9t\u00e9 capable de supprimer la production d'anticorps IgG1 et IgG2a sp\u00e9cifiques anti-HSA chez les souris immunis\u00e9es contre le HAS, ce qui indique sa capacit\u00e9 \u00e0 moduler les r\u00e9ponses Th1 et Th2\", affirme Sartim.<\/p>\n\n\n\n<h2><strong>Impact et performance des documents<\/strong><\/h2>\n\n\n\n<p>Nous pouvons analyser avec <a href=\"https:\/\/mindthegraph.com\/blog\/altmetric\/\" target=\"_blank\" rel=\"noreferrer noopener\">Altmetric<\/a> donn\u00e9es que cet article a eu plus de citations <strong>que <strong>84%<\/strong><\/strong> <strong>d'autres articles de Springer Nature.<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\"><img decoding=\"async\" loading=\"lazy\" width=\"322\" height=\"578\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\" alt=\"\" class=\"wp-image-20254\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png 322w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-167x300.png 167w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-7x12.png 7w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-56x100.png 56w\" sizes=\"(max-width: 322px) 100vw, 322px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Source : <a href=\"https:\/\/citations.springernature.com\/item?doi=10.1186\/s40409-018-0178-3&amp;start=11&amp;years=&amp;journals=&amp;books=&amp;authors=\" target=\"_blank\" rel=\"noreferrer noopener\">Crossref<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Utilisez la puissance des infographies pour dynamiser et <a href=\"https:\/\/mindthegraph.com\/blog\/research-journal-impact-factor\/\">l'impact de votre article<\/a> \u00e9galement. Essayez Mind the Graph !<\/p>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/app\/auth\/register?from_url=\/\" style=\"border-radius:100px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Essayez Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:46px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Il pourrait \u00eatre un peu difficile d'expliquer la modulation anti-inflammatoire de la crotoxine sans les images appropri\u00e9es, mais Mind the Graph existe !<\/p>","protected":false},"author":29,"featured_media":20047,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - 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