{"id":16662,"date":"2022-09-22T19:23:00","date_gmt":"2022-09-22T22:23:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16662"},"modified":"2023-03-17T14:46:01","modified_gmt":"2023-03-17T17:46:01","slug":"success-case-nmda-receptor-adjusted-co-administration-of-ecstasy-and-cannabinoid-receptor-1-agonist","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/fi\/menestys-tapaus-nmda-reseptori-sovitettu-ko-hoito-ekstaasi-ja-kannabinoidireseptori-1-agonisti\/","title":{"rendered":"NMDA-reseptorin s\u00e4\u00e4t\u00e4m\u00e4 ekstaasin ja kannabinoidireseptori-1-agonistin samanaikainen anto amygdalassa BDNF\/Trk-B\/CREB-reitin stimulaation kautta aikuisilla urosrotilla Paperikatsaus"},"content":{"rendered":"<p>Graafisista tiivistelmist\u00e4 on tulossa eritt\u00e4in suosittuja tutkijoiden keskuudessa. Toisin sanoen kirjoittaja loi yhden h\u00e4mm\u00e4stytt\u00e4v\u00e4n mallin selitt\u00e4\u00e4kseen koko t\u00e4m\u00e4n artikkelin pointin tarkkojen kuvien avulla.<\/p>\n\n\n\n<p>Tarkista t\u00e4ydellinen <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0361923016303756\" target=\"_blank\" rel=\"noreferrer noopener\">alkuper\u00e4inen artikkeli<\/a>.<\/p>\n\n\n\n<h2><strong>Selektiivisen CB-1-agonistin, kuten ACPA:n, k\u00e4ytt\u00f6 suojaa neuroneja MDMA-toksisuudelta amygdalassa.<\/strong><\/h2>\n\n\n\n<p>Teoksessa \"NMDA-reseptorin s\u00e4\u00e4t\u00e4m\u00e4 ekstaasin ja kannabinoidireseptori-1-agonistin samanaikainen antaminen amygdalassa BDNF \/ Trk-B \/ CREB-reitin stimulaation kautta aikuisilla urosrotilla\" Ashabi ja kollegat (2017) totesivat, ett\u00e4 NMDA-salpaaminen v\u00e4hensi hermosolujen ampumisnopeutta ja tyrosiinikinaasi B \/ aivojen neurotrofisen tekij\u00e4n \/ CAMP-vaste-elementti\u00e4 sitovan proteiinin tasoa MDMA: ssa ja CB1-reseptoriagonistilla yhdess\u00e4 ruiskutetuissa rotissa. <\/p>\n\n\n\n<p>Glutamaterginen j\u00e4rjestelm\u00e4 s\u00e4\u00e4telee MDMA:n ja ACPA:n yhdistelm\u00e4n suojaavaa vaikutusta TrK-B-reseptorien kautta.<\/p>\n\n\n\n<h2><strong>Mind the Graph:n k\u00e4ytt\u00e4m\u00e4t graafiset tiivistelm\u00e4t<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"835\" height=\"305\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png\" alt=\"\" class=\"wp-image-20094\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png 835w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-300x110.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-768x281.png 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-18x7.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-100x37.png 100w\" sizes=\"(max-width: 835px) 100vw, 835px\" \/><figcaption class=\"wp-element-caption\"><em>Valmistettu&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<p>CB1-reseptorin aktivointi tai MDMA:n induktio v\u00e4hensi hermosolujen laukaisunopeutta. N\u00e4iden kahden l\u00e4\u00e4kkeen samanaikainen injektio lis\u00e4si neuronisolujen selviytymist\u00e4, ja n\u00e4m\u00e4 tapahtumat kumottiin NMDA-reseptoriantagonistilla. <\/p>\n\n\n\n<p>Glutamatergisten reseptoreiden suojaava rooli saattaa todenn\u00e4k\u00f6isesti perustua BDNF\/Trk-B-reittien aktivointiin. <\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"718\" height=\"512\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png\" alt=\"\" class=\"wp-image-20093\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png 718w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-300x214.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-18x12.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-100x71.png 100w\" sizes=\"(max-width: 718px) 100vw, 718px\" \/><figcaption class=\"wp-element-caption\"><em>Valmistettu&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<h2><strong>Paperit Vaikutus ja suorituskyky<\/strong><\/h2>\n\n\n\n<p>Valitsemalla yhden vuoden mittaustulosten vertailun muihin artikkeleihin\/katsauksiin, jotka on julkaistu samana kalenterivuonna kyseisess\u00e4 lehdess\u00e4, voidaan havaita, ett\u00e4 <strong>t\u00e4t\u00e4 artikkelia siteerattiin enemm\u00e4n kuin 47%:t\u00e4 niist\u00e4.<\/strong>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"377\" height=\"330\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png\" alt=\"\" class=\"wp-image-20096\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png 377w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-300x263.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-14x12.png 14w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-100x88.png 100w\" sizes=\"(max-width: 377px) 100vw, 377px\" \/><\/figure>\n\n\n\n<p>Hy\u00f6dynn\u00e4 infografiikan voimaa my\u00f6s artikkelisi tehostamiseen. Kokeile Mind the Graph:t\u00e4!<\/p>","protected":false},"excerpt":{"rendered":"<p>Opi niiden kanssa, jotka ovat jo l\u00f6yt\u00e4neet infografiikan voiman. T\u00e4ss\u00e4 artikkelissa on Mind the Graph:ll\u00e4 tehtyj\u00e4 graafisia tiivistelmi\u00e4. <\/p>","protected":false},"author":29,"featured_media":20081,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NMDA receptor adjusted co-administration of ecstasy and cannabinoid receptor-1 agonist in the amygdala via stimulation of BDNF\/Trk-B\/CREB pathway in adult male rats Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Learn with the ones who already discovered the power of infographics. 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