{"id":16657,"date":"2022-09-14T13:04:15","date_gmt":"2022-09-14T16:04:15","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16657"},"modified":"2023-03-17T14:47:26","modified_gmt":"2023-03-17T17:47:26","slug":"success-case-xtalkdb-a-database-of-signaling-pathway-crosstalk","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/es\/success-case-xtalkdb-a-database-of-signaling-pathway-crosstalk\/","title":{"rendered":"XTALKDB: una base de datos de cruces de v\u00edas de se\u00f1alizaci\u00f3n Revisi\u00f3n de documentos"},"content":{"rendered":"

Este asombroso art\u00edculo saca a relucir las estad\u00edsticas que resumen los datos de XTALKDB. En pocos minutos, el autor cre\u00f3 una infograf\u00eda que explica la distribuci\u00f3n de las especies en XTALKDB.<\/p>\n\n\n\n

Compruebe el art\u00edculo original aqu\u00ed<\/a>.<\/p>\n\n\n\n

Como los seres humanos son criaturas visuales, las im\u00e1genes siguen siendo la mejor manera de explicar su investigaci\u00f3n con todos los detalles que desee.<\/p>\n\n\n\n

Los cient\u00edficos han desarrollado una base de datos que documenta la interrelaci\u00f3n entre pares espec\u00edficos de v\u00edas de se\u00f1alizaci\u00f3n y las especies y tejidos en los que se observan<\/strong><\/h2>\n\n\n\n

Un grupo de investigaci\u00f3n dirigido por Sarah Sam, del Departamento de Ciencias Biol\u00f3gicas (2016), inform\u00f3 de que la percepci\u00f3n de una se\u00f1al externa por parte de los receptores hace que cambien las actividades de las prote\u00ednas intermedias. <\/p>\n\n\n\n

Esto da lugar a la regulaci\u00f3n de los factores de transcripci\u00f3n, que modulan la expresi\u00f3n de los genes objetivo. Para cada par de v\u00edas, XTalkDB registra informaci\u00f3n detallada que describe las condiciones experimentales en las que se descubri\u00f3 la diafon\u00eda. <\/p>\n\n\n\n

Las c\u00e9lulas eval\u00faan y responden a su entorno mediante v\u00edas de se\u00f1alizaci\u00f3n. Una v\u00eda de se\u00f1alizaci\u00f3n suele contener un conjunto bien definido de interacciones reguladoras y f\u00edsicas entre receptores, prote\u00ednas de se\u00f1alizaci\u00f3n intermedias, factores de transcripci\u00f3n y genes diana. <\/p>\n\n\n\n

El sitio web XTalkDB ofrece una interfaz f\u00e1cil de usar para que los cient\u00edficos puedan buscar informaci\u00f3n sobre la diafon\u00eda consultando una o varias v\u00edas o mol\u00e9culas de inter\u00e9s.<\/p>\n\n\n\n

En el estudio se incluyeron 650 parejas.<\/strong><\/p>\n\n\n\n

Resumen gr\u00e1fico con tecnolog\u00eda Mind the Graph<\/strong><\/h2>\n\n\n
\n
\"success-case-XTALKDB-a-database-of-signaling-pathway-crosstalk\"<\/a>
Hecho con Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

En cuanto a las posibles mejoras, \"el proceso de curaci\u00f3n manual en el que se basa XTalkDB tiene sus limitaciones, sobre todo cuando intentamos ampliar la cobertura de la base de datos. <\/p>\n\n\n\n

Tenemos previsto desarrollar un marco de procesamiento del lenguaje natural que califique las publicaciones en funci\u00f3n de su probabilidad de documentar la diafon\u00eda. As\u00ed, un conservador podr\u00e1 centrarse en las publicaciones mejor clasificadas\", admiten.<\/p>\n\n\n\n

Papeles Impacto y rendimiento<\/strong><\/h2>\n\n\n\n

Podemos analizar con Altmetric<\/a> datos que este documento est\u00e1 en el parte superior de todas las m\u00e9tricas dentro de todos los art\u00edculos financiados por los NIH en las Dimensiones. <\/strong><\/p>\n\n\n

\n
\"\"<\/a>
Fuente: https:\/\/badge.dimensions.ai\/details\/id\/pub.1052462103<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Utiliza el poder de la infograf\u00eda para potenciar tambi\u00e9n tu art\u00edculo. \u00a1Pruebe Mind the Graph!<\/p>\n\n\n\n

<\/div>\n\n\n\n
\n
Prueba Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

Aprende con los que ya han descubierto el poder de la infograf\u00eda. Este art\u00edculo tiene res\u00famenes gr\u00e1ficos realizados con Mind the Graph. <\/p>","protected":false},"author":29,"featured_media":20046,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"\nXTALKDB: a database of signaling pathway crosstalk Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"This amazing article brings out statistics summarizing data in XTALKDB with an infographic explaining the distribution of the species in XTALKDB.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/es\/success-case-xtalkdb-a-database-of-signaling-pathway-crosstalk\/\" \/>\n<meta property=\"og:locale\" content=\"es_MX\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"XTALKDB: a database of signaling pathway crosstalk Paper Review - 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