{"id":16651,"date":"2022-09-12T18:50:00","date_gmt":"2022-09-12T21:50:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16651"},"modified":"2023-03-17T14:47:35","modified_gmt":"2023-03-17T17:47:35","slug":"success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/es\/caso-de-exito-potencial-inmunoterapeutico-de-la-crotoxina-propiedades-antiinflamatorias-inmunosupresoras\/","title":{"rendered":"Potencial inmunoterap\u00e9utico de la crotoxina: propiedades antiinflamatorias e inmunosupresoras Paper Review"},"content":{"rendered":"<p>Podr\u00eda ser un poco dif\u00edcil explicar la modulaci\u00f3n antiinflamatoria de la crotoxina sin las im\u00e1genes adecuadas, \u00a1pero para eso existe Mind the Graph!<\/p>\n\n\n\n<h2><strong>Una revisi\u00f3n de la investigaci\u00f3n cient\u00edfica sobre la crotoxina, un veneno de la serpiente de cascabel<\/strong><\/h2>\n\n\n\n<p>En 'Immunotherapeutic potential of Crotoxin', Marco Sartim et al. (2018) se\u00f1alaron que durante los \u00faltimos 80 a\u00f1os, la crotoxina se ha convertido en una de las toxinas aisladas m\u00e1s investigadas de los venenos de serpiente. <\/p>\n\n\n\n<p>La crotoxina es el principal componente t\u00f3xico del veneno de la serpiente de cascabel sudamericana Crotalus durissus terrificus. Los estudios han demostrado que el efecto inmunomodulador de la C.d.t. est\u00e1 asociado a la producci\u00f3n de mediadores antiinflamatorios. <\/p>\n\n\n\n<p>La capacidad de la crotoxina y sus subunidades para modular el sistema inmunitario introdujo nuevas perspectivas como potenciales agentes terap\u00e9uticos.<\/p>\n\n\n\n<p><strong>Los investigadores revisaron 161 art\u00edculos.<\/strong><\/p>\n\n\n\n<p>Compruebe el <a href=\"https:\/\/jvat.biomedcentral.com\/articles\/10.1186\/s40409-018-0178-3\" target=\"_blank\" rel=\"noreferrer noopener\">art\u00edculo original aqu\u00ed<\/a>.<\/p>\n\n\n\n<h2><strong>Res\u00famenes gr\u00e1ficos con tecnolog\u00eda Mind the Graph<\/strong><\/h2>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"1003\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp\" alt=\"\" class=\"wp-image-20251\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp 1024w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-300x294.webp 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-768x752.webp 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-12x12.webp 12w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-100x98.webp 100w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp 1418w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Hecho con <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>El autor utiliz\u00f3 la plataforma Mind the Graph para crear una figura esquem\u00e1tica sobre la circulaci\u00f3n, los tejidos y los eventos celulares modulados por la Crotoxina y sus subunidades durante el est\u00edmulo inflamatorio.<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML.webp\"><img decoding=\"async\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML-839x1024.webp\" alt=\"\" class=\"wp-image-20252\"\/><\/a><figcaption class=\"wp-element-caption\"><em>Hecho con <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>El autor tambi\u00e9n detall\u00f3 la circulaci\u00f3n sangu\u00ednea, la localizaci\u00f3n de los linfocitos en los ganglios linf\u00e1ticos y los acontecimientos celulares asociados a los efectos inmunosupresores de la crotoxina y sus subunidades.<\/p>\n\n\n\n<p><strong>Este es el poder de la infograf\u00eda.<\/strong><\/p>\n\n\n\n<p>Las conclusiones de los autores parecen consolidar trabajos anteriores en este \u00e1mbito: \"La crotoxina fue capaz de suprimir la producci\u00f3n de anticuerpos espec\u00edficos anti-HSA IgG1 e IgG2a de ratones inmunizados con HAS, lo que indica su capacidad para modular las respuestas Th1 y Th2\", afirm\u00f3 Sartim.<\/p>\n\n\n\n<h2><strong>Papeles Impacto y rendimiento<\/strong><\/h2>\n\n\n\n<p>Podemos analizar con <a href=\"https:\/\/mindthegraph.com\/blog\/altmetric\/\" target=\"_blank\" rel=\"noreferrer noopener\">Altmetric<\/a> datos de que este documento ten\u00eda m\u00e1s citas <strong>que <strong>84%<\/strong><\/strong> <strong>de otros art\u00edculos de Springer Nature.<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\"><img decoding=\"async\" loading=\"lazy\" width=\"322\" height=\"578\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\" alt=\"\" class=\"wp-image-20254\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png 322w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-167x300.png 167w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-7x12.png 7w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-56x100.png 56w\" sizes=\"(max-width: 322px) 100vw, 322px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Fuente <a href=\"https:\/\/citations.springernature.com\/item?doi=10.1186\/s40409-018-0178-3&amp;start=11&amp;years=&amp;journals=&amp;books=&amp;authors=\" target=\"_blank\" rel=\"noreferrer noopener\">Crossref<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Utilice el poder de la infograf\u00eda para impulsar y <a href=\"https:\/\/mindthegraph.com\/blog\/research-journal-impact-factor\/\">impacto de su art\u00edculo<\/a> tambi\u00e9n. \u00a1Prueba Mind the Graph!<\/p>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/app\/auth\/register?from_url=\/\" style=\"border-radius:100px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Prueba Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:46px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Podr\u00eda ser un poco dif\u00edcil explicar la modulaci\u00f3n antiinflamatoria de la crotoxina sin las im\u00e1genes adecuadas, \u00a1pero el Mind the Graph existe!<\/p>","protected":false},"author":29,"featured_media":20047,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Immunotherapeutic potential of Crotoxin: anti-inflammatory and immunosuppressive properties Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"It could be a little difficult to explain the crotoxin\u2019s anti-inflammatory modulation without the proper images, but Mind the Graph exists!\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, 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