{"id":16651,"date":"2022-09-12T18:50:00","date_gmt":"2022-09-12T21:50:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16651"},"modified":"2023-03-17T14:47:35","modified_gmt":"2023-03-17T17:47:35","slug":"success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/de\/erfolgsfall-immuntherapeutisches-potenzial-von-krotoxin-entzundungshemmenden-und-immunosuppressiven-eigenschaften\/","title":{"rendered":"Immuntherapeutisches Potenzial von Crotoxin: entz\u00fcndungshemmende und immunsuppressive Eigenschaften \u00dcbersichtsarbeit"},"content":{"rendered":"<p>Es k\u00f6nnte etwas schwierig sein, die entz\u00fcndungshemmende Modulation des Crotoxins ohne die richtigen Bilder zu erkl\u00e4ren, aber daf\u00fcr gibt es ja Mind the Graph!<\/p>\n\n\n\n<h2><strong>Ein \u00dcberblick \u00fcber die wissenschaftliche Forschung zu Crotoxin, einem Gift der Klapperschlange<\/strong><\/h2>\n\n\n\n<p>In \"Immunotherapeutic potential of Crotoxin\" stellen Marco Sartim et al. (2018) fest, dass Crotoxin in den letzten 80 Jahren zu einem der am meisten untersuchten isolierten Toxine aus Schlangengiften geworden ist. <\/p>\n\n\n\n<p>Crotoxin ist der wichtigste toxische Bestandteil des Giftes der s\u00fcdamerikanischen Klapperschlange Crotalus durissus terrificus. Studien haben gezeigt, dass die immunmodulatorische Wirkung von Crotoxin mit der Produktion von entz\u00fcndungshemmenden Mediatoren zusammenh\u00e4ngt. <\/p>\n\n\n\n<p>Die F\u00e4higkeit von Crotoxin und seinen Untereinheiten, das Immunsystem zu modulieren, er\u00f6ffnet neue Perspektiven als potenzielle Therapeutika.<\/p>\n\n\n\n<p><strong>Die Forscher untersuchten 161 Artikel.<\/strong><\/p>\n\n\n\n<p>Pr\u00fcfen Sie die <a href=\"https:\/\/jvat.biomedcentral.com\/articles\/10.1186\/s40409-018-0178-3\" target=\"_blank\" rel=\"noreferrer noopener\">Originalartikel hier<\/a>.<\/p>\n\n\n\n<h2><strong>Grafische Zusammenfassungen auf der Grundlage von Mind the Graph<\/strong><\/h2>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"1003\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp\" alt=\"\" class=\"wp-image-20251\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp 1024w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-300x294.webp 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-768x752.webp 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-12x12.webp 12w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-100x98.webp 100w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp 1418w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Hergestellt mit <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Der Autor nutzte die Mind the Graph-Plattform, um eine schematische Darstellung der Zirkulation, des Gewebes und der zellul\u00e4ren Ereignisse zu erstellen, die durch Crotoxin und seine Untereinheiten w\u00e4hrend des Entz\u00fcndungsreizes moduliert werden.<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML.webp\"><img decoding=\"async\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML-839x1024.webp\" alt=\"\" class=\"wp-image-20252\"\/><\/a><figcaption class=\"wp-element-caption\"><em>Hergestellt mit <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Der Autor ging auch ausf\u00fchrlich auf den Blutkreislauf, die Ansiedlung von Lymphozyten in den Lymphknoten und die zellul\u00e4ren Vorg\u00e4nge im Zusammenhang mit den immunsuppressiven Wirkungen von Crotoxin und seinen Untereinheiten ein.<\/p>\n\n\n\n<p><strong>Das ist die Macht der Infografik!<\/strong><\/p>\n\n\n\n<p>Die Schlussfolgerungen der Autoren scheinen fr\u00fchere Arbeiten in diesem Bereich zu konsolidieren: \"Crotoxin war in der Lage, die Produktion spezifischer Anti-HSA-IgG1- und IgG2a-Antik\u00f6rper bei HAS-immunisierten M\u00e4usen zu unterdr\u00fccken, was auf seine F\u00e4higkeit hinweist, Th1- und Th2-Reaktionen zu modulieren\", so Sartim.<\/p>\n\n\n\n<h2><strong>Papiere Wirkung und Leistung<\/strong><\/h2>\n\n\n\n<p>Wir k\u00f6nnen analysieren mit <a href=\"https:\/\/mindthegraph.com\/blog\/altmetric\/\" target=\"_blank\" rel=\"noreferrer noopener\">Altmetric<\/a> Daten, dass diese Arbeit mehr Zitate hatte <strong>als <strong>84%<\/strong><\/strong> <strong>von anderen Artikeln aus Springer Nature.<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\"><img decoding=\"async\" loading=\"lazy\" width=\"322\" height=\"578\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\" alt=\"\" class=\"wp-image-20254\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png 322w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-167x300.png 167w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-7x12.png 7w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-56x100.png 56w\" sizes=\"(max-width: 322px) 100vw, 322px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Quelle <a href=\"https:\/\/citations.springernature.com\/item?doi=10.1186\/s40409-018-0178-3&amp;start=11&amp;years=&amp;journals=&amp;books=&amp;authors=\" target=\"_blank\" rel=\"noreferrer noopener\">Querverweis<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Nutzen Sie die Kraft von Infografiken, um die <a href=\"https:\/\/mindthegraph.com\/blog\/research-journal-impact-factor\/\">Ihren Artikel beeinflussen<\/a> auch. Versuchen Sie Mind the Graph!<\/p>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/app\/auth\/register?from_url=\/\" style=\"border-radius:100px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Versuchen Sie Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:46px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Es k\u00f6nnte etwas schwierig sein, die entz\u00fcndungshemmende Modulation des Crotoxins ohne die richtigen Bilder zu erkl\u00e4ren, aber Mind the Graph existiert!<\/p>","protected":false},"author":29,"featured_media":20047,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - 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