{"id":8728,"date":"2019-04-23T16:35:01","date_gmt":"2019-04-23T19:35:01","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=8728"},"modified":"2022-10-18T08:23:59","modified_gmt":"2022-10-18T11:23:59","slug":"visual-abstract-example","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/da\/visuelt-abstrakt-eksempel\/","title":{"rendered":"Visuelt abstrakt oprettet af brugeren til at forklare forskningsartiklen \"Optimized Small-Molecule Pull-Downs Define MLBP1 as an Acyl-Lipid-Binding Protein\" af Yelena Sterlin."},"content":{"rendered":"

Et visuelt abstrakt er ikke let at skabe, men det er kommet for at blive. S\u00e5 vi elsker altid at vise vores brugeres fantastiske arbejde frem som et inspirerende eksempel p\u00e5 visuelt abstrakt. Vi \u00f8nsker at give forskere mulighed for at skabe en mere visuel og tilg\u00e6ngelig videnskab.<\/p>\n

I indl\u00e6gget vil jeg vise dig lidt af den oprindelige forskning fra Yelena Sterlin<\/a> og kolleger. Hun er ph.d.-studerende ved fakultetet for landbrug, f\u00f8devarer og milj\u00f8 p\u00e5 Hebrew University of Jerusalem.<\/p>\n

Hendes nye artikel Optimerede sm\u00e5molekyle pull-downs definerer MLBP1 som et acyl-lipid-bindende protein<\/a> <\/strong>s\u00e6tter fokus p\u00e5 protein-metabolit-interaktioner i planter, med fokus p\u00e5 abscisinsyre (ABA)-receptorer. Hun abonnerer ogs\u00e5 p\u00e5 Mind the Graph, s\u00e5 hun har lavet en infografik i Husk grafen<\/a> til at forklare deres metode.<\/p>\n

Betydningen af START-dom\u00e6ne-relaterede proteiner<\/strong><\/h2>\n

 <\/p>\n

If\u00f8lge Naturmagasinet<\/a>Abscisinsyre (ABA) er det vigtigste fytohormon, der er involveret i abiotisk stressrespons og dets tilpasning. Det er ogs\u00e5 et agrikemisk kandidatstof. ABA blev f\u00f8rst opdaget i 1960'erne. Siden da har det vist sig at v\u00e6re en vigtig regulator af s\u00e5 forskellige processer som dvale, spiring, fr\u00f8udvikling og reaktioner p\u00e5 biotisk og abiotisk stress.<\/p>\n

De tidligste begivenheder, der involverer ABA-signalvejen, involverer ABA-binding til PYR\/PYL\/RCARs-receptorer. Receptorerne h\u00f8rer til START-dom\u00e6ne-superfamilien.<\/p>\n

START-proteindom\u00e6nerne er et lipidbindende dom\u00e6ne, der findes i genomer fra bakterier, protister, g\u00e6r, planter og dyr. De er dog mere almindelige i planter. I henhold til Schrick<\/a>Tilstedev\u00e6relsen af START-dom\u00e6ner i evolution\u00e6rt fjerne arter som dyr og planter tyder p\u00e5 en konserveret mekanisme for interaktion mellem proteiner og lipider\/steroler.<\/p>\n

Artiklen er udgivet i Plantejournalen<\/a> fokuserer p\u00e5 PYR\/PYL\/RCARs ABA-receptorer. Forskerne besluttede at optimere en metode til identifikation af START-dom\u00e6ne og START-dom\u00e6ne-relaterede proteinligander i planter, fordi \"START-dom\u00e6neproteinliganderne er uundv\u00e6rlige for, at deres protein fungerer korrekt b\u00e5de i dyr og planter, og det blev p\u00e5vist, at START-dom\u00e6neproteiner i planter er involveret i vigtige fysiologiske processer.\"<\/em><\/p>\n

Et visuelt sammendrag af metoden<\/strong><\/h2>\n

 <\/p>\n

For at forklare deres metode har forskerne lavet en infografik med grafillustrationer. Det er i\u00f8jnefaldende og lettere at forst\u00e5. <\/strong><\/h4>\n

 <\/p>\n

Infografikken nedenfor viser den eksperimentelle arbejdsgang. Som du kan se, har de udtrykt og oprenset fire START-proteiner. De filtrerede og inkuberede supernatanten, der indeholdt den native opl\u00f8selige fraktion, ved hj\u00e6lp af streptavidin-sepharose, en affinitetsresin til p\u00e5lidelige og h\u00f8je-opl\u00f8sningsrensning af biomolekyler. Derefter analyserede de aliquoter ved hj\u00e6lp af western blot. For at identificere liganden eluerede de formodede ligander og udsatte dem for en LC -MS (v\u00e6skekromatografi og massespektrometri) systemanalyse. De molekyl\u00e6re strukturer af de formodede ligander af interesse blev bestemt ved tandem-massespektrometri.<\/p>\n

 <\/p>\n

\"visuelt<\/p>\n

Forfatterne pr\u00e6senterede en god teknik til indledende sondering af proteinligander i planter. De tilpassede fremgangsm\u00e5den til at opdage START-ligander. Man kan dog tilpasse metoden til ligander af forskellig kemisk natur ved at justere de analytiske betingelser.<\/p>\n

Hvis du vil vise din forskning ved hj\u00e6lp af videnskabelige illustrationer og visuelle abstracts, kan du ogs\u00e5 bruge Mind the Graph. S\u00e5 er du klar til at forbedre din kommunikation inden for videnskab?<\/p>\n

\"preview_250\"<\/a><\/p>","protected":false},"excerpt":{"rendered":"

Et visuelt abstrakt er ikke let at skabe, men det er kommet for at blive. S\u00e5 vi elsker altid at vise vores brugeres fantastiske arbejde frem som et inspirerende eksempel p\u00e5 visuelt abstrakt. Vi \u00f8nsker at give forskere mulighed for at skabe en mere visuel og tilg\u00e6ngelig videnskab. I indl\u00e6gget vil jeg vise dig lidt af det [...]<\/p>","protected":false},"author":11,"featured_media":8741,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[193,40],"tags":[291,96,292,245,294,295,554,775,293,382],"yoast_head":"\nVisual abstract created by Mind the Graph user. Attractive scientific figure!<\/title>\n<meta name=\"description\" content=\"See the visual abstract created by the MindtheGraph subscriber Yelena Sterling to explain her research in an attractive and instructive way. Awesome job!\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/da\/visuel-abstrakt\/visual-abstract-example\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Visual abstract created by Mind the Graph user. Attractive scientific figure!\" \/>\n<meta property=\"og:description\" content=\"See the visual abstract created by the MindtheGraph subscriber Yelena Sterling to explain her research in an attractive and instructive way. Awesome job!\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/da\/visuel-abstrakt\/visual-abstract-example\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2019-04-23T19:35:01+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-10-18T11:23:59+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2019\/04\/cover-yelena.png\" \/>\n\t<meta property=\"og:image:width\" content=\"622\" \/>\n\t<meta property=\"og:image:height\" content=\"379\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Fabiola Soares\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Fabiola Soares\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Visual abstract created by Mind the Graph user. Attractive scientific figure!","description":"See the visual abstract created by the MindtheGraph subscriber Yelena Sterling to explain her research in an attractive and instructive way. Awesome job!","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mindthegraph.com\/blog\/da\/visuel-abstrakt\/visual-abstract-example\/","og_locale":"da_DK","og_type":"article","og_title":"Visual abstract created by Mind the Graph user. Attractive scientific figure!","og_description":"See the visual abstract created by the MindtheGraph subscriber Yelena Sterling to explain her research in an attractive and instructive way. Awesome job!","og_url":"https:\/\/mindthegraph.com\/blog\/da\/visuel-abstrakt\/visual-abstract-example\/","og_site_name":"Mind the Graph Blog","article_published_time":"2019-04-23T19:35:01+00:00","article_modified_time":"2022-10-18T11:23:59+00:00","og_image":[{"width":622,"height":379,"url":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2019\/04\/cover-yelena.png","type":"image\/png"}],"author":"Fabiola Soares","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Fabiola Soares","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/mindthegraph.com\/blog\/fi\/visual-abstract-example\/","url":"https:\/\/mindthegraph.com\/blog\/fi\/visual-abstract-example\/","name":"Visual abstract created by Mind the Graph user. Attractive scientific figure!","isPartOf":{"@id":"https:\/\/mindthegraph.com\/blog\/#website"},"datePublished":"2019-04-23T19:35:01+00:00","dateModified":"2022-10-18T11:23:59+00:00","author":{"@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/5592c012d89648325be9b0f3c3f91132"},"description":"See the visual abstract created by the MindtheGraph subscriber Yelena Sterling to explain her research in an attractive and instructive way. Awesome job!","breadcrumb":{"@id":"https:\/\/mindthegraph.com\/blog\/fi\/visual-abstract-example\/#breadcrumb"},"inLanguage":"da-DK","potentialAction":[{"@type":"ReadAction","target":["https:\/\/mindthegraph.com\/blog\/fi\/visual-abstract-example\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/mindthegraph.com\/blog\/fi\/visual-abstract-example\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/mindthegraph.com\/blog\/"},{"@type":"ListItem","position":2,"name":"Visual abstract created by user to explain the research paper “Optimized Small\u2010Molecule Pull\u2010Downs Define MLBP1 as an Acyl\u2010Lipid\u2010Binding Protein” by Yelena Sterlin"}]},{"@type":"WebSite","@id":"https:\/\/mindthegraph.com\/blog\/#website","url":"https:\/\/mindthegraph.com\/blog\/","name":"Mind the Graph Blog","description":"Your science can be beautiful!","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/mindthegraph.com\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"da-DK"},{"@type":"Person","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/5592c012d89648325be9b0f3c3f91132","name":"Fabiola Soares","image":{"@type":"ImageObject","inLanguage":"da-DK","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/7dca2c6a766aff1db898cc74c18284d8?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/7dca2c6a766aff1db898cc74c18284d8?s=96&d=mm&r=g","caption":"Fabiola Soares"},"url":"https:\/\/mindthegraph.com\/blog\/da\/author\/fabiola\/"}]}},"_links":{"self":[{"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/posts\/8728"}],"collection":[{"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/comments?post=8728"}],"version-history":[{"count":23,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/posts\/8728\/revisions"}],"predecessor-version":[{"id":14568,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/posts\/8728\/revisions\/14568"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/media\/8741"}],"wp:attachment":[{"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/media?parent=8728"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/categories?post=8728"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/tags?post=8728"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}