{"id":6300,"date":"2016-10-04T14:25:20","date_gmt":"2016-10-04T17:25:20","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=6300"},"modified":"2022-10-18T08:10:46","modified_gmt":"2022-10-18T11:10:46","slug":"autophagy-wins-nobel-prize-medicine","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/da\/autofagi-vinder-nobelpris-medicin\/","title":{"rendered":"Autofagi vinder Nobelprisen i medicin"},"content":{"rendered":"

Autofagiprocessen er involveret i flere tilstande som f.eks. kr\u00e6ft og neurologiske sygdomme. Den fungerer som kroppens interne genbrugsprogram. Men en forstyrret autofagi er blevet sat i forbindelse med Parkinsons sygdom, diabetes, kr\u00e6ft og andre aldersrelaterede lidelser.<\/p>\n

Efter denne lille introduktion til vigtigheden af autofagiprocessen er det ikke overraskende, at nye opdagelser p\u00e5 dette omr\u00e5de kan f\u00f8re til en Nobelpris. I mandags vandt forskeren Yoshino Ohsumi s\u00e5ledes Nobelprisen i Nobelprisen i medicin<\/a> for at identificere de f\u00f8rste essentielle gener for autofagi.<\/p>\n

\"Jeg har det ikke godt med at konkurrere med mange mennesker, og i stedet synes jeg, det er sjovere at g\u00f8re noget, som ingen andre g\u00f8r. P\u00e5 en m\u00e5de er det, hvad videnskab handler om, og gl\u00e6den ved at finde noget inspirerer mig.\" Yoshino Ohsumi <\/a><\/p><\/blockquote>\n

Hvordan gjorde Ohsumi det?<\/h3>\n

I sit laboratorium havde Ohsumi konstrueret g\u00e6rstammer, der akkumulerede autofagosomer under sult. Denne akkumulering kunne kun ske, hvis essentielle gener for autofagi var inaktive. Derfor begyndte Ohsumi at manipulere cellerne med flere genmutationer, og det lykkedes ham at fremkalde autofagi.<\/p>\n

\"Autofagi<\/a><\/p>\n

Autofagi har eksisteret l\u00e6nge<\/h3>\n

Selvom autofagi har v\u00e6ret kendt i de sidste 50 \u00e5r, var det f\u00f8rst i 1990'erne med Ohsumis studier, at denne proces' betydning blev anerkendt.
\nOhsumi har allerede f\u00e5et en del fans for sit arbejde:<\/p>\n

\"Autofagi<\/a><\/p>\n

\n

\"Jeg er meget glad for, at han har f\u00e5et dette \u00e5rs Nobelpris, det er meget velfortjent. Hans laboratorium arbejder hovedsageligt med g\u00e6r. De foretog de indledende screeninger, der gjorde det muligt at opdage de vigtige gener, der er involveret i autofagi. S\u00e5 mange andre laboratorier har udnyttet hans opdagelser, direkte eller indirekte, for at se, hvorfor det er vigtigt i forbindelse med sygdomme.\"<\/p>\n

David Rubinsztein<\/a> - vicedirekt\u00f8r for Cambridge Institute for Medical Research<\/p>\n<\/blockquote>\n

\"Autofagi<\/a><\/p>\n

\n

\"Jeg synes, det er meget vigtigt, at dette omr\u00e5de af videnskaben bliver anerkendt. Det vigtige princip her er at g\u00e5 efter f\u00e6lles mekanismer i sygdomme. Det \u00e5bner muligheder for at behandle disse lidelser, som er anderledes end mere konventionelle sygdomsspecifikke tilgange.\"<\/p>\n

Giovanna Mallucci<\/a> - professor i klinisk neurovidenskab ved University of Cambridge<\/p>\n<\/blockquote>\n

\"Autofagi<\/a><\/p>","protected":false},"excerpt":{"rendered":"

Autofagiprocessen er involveret i flere tilstande som f.eks. kr\u00e6ft og neurologiske sygdomme. Den fungerer som kroppens interne genbrugsprogram. Imidlertid er en forstyrret autofagi blevet sat i forbindelse med Parkinsons sygdom, diabetes, kr\u00e6ft og andre aldersrelaterede lidelser. Efter denne lille introduktion til vigtigheden af autofagiprocessen er det ingen overraskelse, at nye opdagelser [...]<\/p>","protected":false},"author":11,"featured_media":6304,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[959,28],"tags":[554],"yoast_head":"\nAutophagy wins Nobel Prize in medicine - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\""I find it more enjoyable doing something nobody else is doing. In a way, that\u2019s what science is all about" Yoshino Ohsumi about his research on autophagy.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/da\/autofagi-vinder-nobelpris-medicin\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Autophagy wins Nobel Prize in medicine - Mind the Graph Blog\" \/>\n<meta property=\"og:description\" content=\""I find it more enjoyable doing something nobody else is doing. In a way, that\u2019s what science is all about" Yoshino Ohsumi about his research on autophagy.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/da\/autofagi-vinder-nobelpris-medicin\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2016-10-04T17:25:20+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-10-18T11:10:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/ohsumi-a-professor-in-tokyo-institute-of-technology-is-seen-at-his-laboratory-office-in-yokohama.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2000\" \/>\n\t<meta property=\"og:image:height\" content=\"1125\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Fabiola Soares\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Fabiola Soares\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Autophagy wins Nobel Prize in medicine - Mind the Graph Blog","description":"\"I find it more enjoyable doing something nobody else is doing. In a way, that\u2019s what science is all about\" Yoshino Ohsumi about his research on autophagy.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mindthegraph.com\/blog\/da\/autofagi-vinder-nobelpris-medicin\/","og_locale":"da_DK","og_type":"article","og_title":"Autophagy wins Nobel Prize in medicine - Mind the Graph Blog","og_description":"\"I find it more enjoyable doing something nobody else is doing. In a way, that\u2019s what science is all about\" Yoshino Ohsumi about his research on autophagy.","og_url":"https:\/\/mindthegraph.com\/blog\/da\/autofagi-vinder-nobelpris-medicin\/","og_site_name":"Mind the Graph Blog","article_published_time":"2016-10-04T17:25:20+00:00","article_modified_time":"2022-10-18T11:10:46+00:00","og_image":[{"width":2000,"height":1125,"url":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/ohsumi-a-professor-in-tokyo-institute-of-technology-is-seen-at-his-laboratory-office-in-yokohama.jpg","type":"image\/jpeg"}],"author":"Fabiola Soares","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Fabiola Soares","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/mindthegraph.com\/blog\/autophagy-wins-nobel-prize-medicine\/","url":"https:\/\/mindthegraph.com\/blog\/autophagy-wins-nobel-prize-medicine\/","name":"Autophagy wins Nobel Prize in medicine - Mind the Graph Blog","isPartOf":{"@id":"https:\/\/mindthegraph.com\/blog\/#website"},"datePublished":"2016-10-04T17:25:20+00:00","dateModified":"2022-10-18T11:10:46+00:00","author":{"@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/5592c012d89648325be9b0f3c3f91132"},"description":"\"I find it more enjoyable doing something nobody else is doing. In a way, that\u2019s what science is all about\" Yoshino Ohsumi about his research on autophagy.","breadcrumb":{"@id":"https:\/\/mindthegraph.com\/blog\/autophagy-wins-nobel-prize-medicine\/#breadcrumb"},"inLanguage":"da-DK","potentialAction":[{"@type":"ReadAction","target":["https:\/\/mindthegraph.com\/blog\/autophagy-wins-nobel-prize-medicine\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/mindthegraph.com\/blog\/autophagy-wins-nobel-prize-medicine\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/mindthegraph.com\/blog\/"},{"@type":"ListItem","position":2,"name":"Autophagy wins Nobel Prize in medicine"}]},{"@type":"WebSite","@id":"https:\/\/mindthegraph.com\/blog\/#website","url":"https:\/\/mindthegraph.com\/blog\/","name":"Mind the Graph Blog","description":"Your science can be beautiful!","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/mindthegraph.com\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"da-DK"},{"@type":"Person","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/5592c012d89648325be9b0f3c3f91132","name":"Fabiola Soares","image":{"@type":"ImageObject","inLanguage":"da-DK","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/7dca2c6a766aff1db898cc74c18284d8?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/7dca2c6a766aff1db898cc74c18284d8?s=96&d=mm&r=g","caption":"Fabiola Soares"},"url":"https:\/\/mindthegraph.com\/blog\/da\/author\/fabiola\/"}]}},"_links":{"self":[{"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/posts\/6300"}],"collection":[{"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/comments?post=6300"}],"version-history":[{"count":13,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/posts\/6300\/revisions"}],"predecessor-version":[{"id":6317,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/posts\/6300\/revisions\/6317"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/media\/6304"}],"wp:attachment":[{"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/media?parent=6300"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/categories?post=6300"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/da\/wp-json\/wp\/v2\/tags?post=6300"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}