{"id":16657,"date":"2022-09-14T13:04:15","date_gmt":"2022-09-14T16:04:15","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16657"},"modified":"2023-03-17T14:47:26","modified_gmt":"2023-03-17T17:47:26","slug":"success-case-xtalkdb-a-database-of-signaling-pathway-crosstalk","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/da\/succes-case-xtalkdb-a-database-over-signalveje-crosstalk\/","title":{"rendered":"XTALKDB: en database over signalveje, der krydser hinanden Paper Review"},"content":{"rendered":"

Denne fantastiske artikel bringer statistik, der opsummerer data i XTALKDB. P\u00e5 bare et par minutter har forfatteren lavet en infografik, der forklarer udbredelsen af arterne i XTALKDB.<\/p>\n\n\n\n

Kontroller Originalartikel her<\/a>.<\/p>\n\n\n\n

Da mennesker er visuelle v\u00e6sener, er billeder stadig den bedste m\u00e5de at forklare din forskning p\u00e5 med s\u00e5 mange detaljer, som du \u00f8nsker.<\/p>\n\n\n\n

Forskere har udviklet en database, der dokumenterer krydsfeltet mellem specifikke par af signalveje og de arter og v\u00e6v, hvor de er observeret.<\/strong><\/h2>\n\n\n\n

En forskergruppe ledet af Sarah Sam fra Department of Biological Sciences (2016) rapporterede, at receptorers opfattelse af et eksternt signal f\u00e5r aktiviteten af intermedi\u00e6re proteiner til at \u00e6ndre sig. <\/p>\n\n\n\n

Dette resulterer i regulering af transkriptionsfaktorer, som modulerer udtrykket af m\u00e5lgener. For hvert par af pathways registrerer XTalkDB detaljerede oplysninger, der beskriver de eksperimentelle betingelser, hvorunder crosstalk blev opdaget. <\/p>\n\n\n\n

Celler vurderer og reagerer p\u00e5 deres milj\u00f8 via signalveje. En signalvej indeholder typisk et veldefineret s\u00e6t af regulatoriske og fysiske interaktioner mellem receptorer, intermedi\u00e6re signalproteiner, transkriptionsfaktorer og m\u00e5lgener. <\/p>\n\n\n\n

XTalkDB-hjemmesiden giver forskere en brugervenlig gr\u00e6nseflade til at gennemse oplysninger om krydstale ved at foresp\u00f8rge p\u00e5 en eller flere veje eller molekyler af interesse.<\/p>\n\n\n\n

Der indgik 650 par i unders\u00f8gelsen.<\/strong><\/p>\n\n\n\n

Grafisk abstrakt drevet af Mind the Graph<\/strong><\/h2>\n\n\n
\n
\"succes-sag-XTALKDB-en-database-over-signalveje-crosstalk\"<\/a>
Fremstillet med Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Om mulige forbedringer siger han: \"Den manuelle kurateringsproces, der ligger til grund for XTalkDB, har sine begr\u00e6nsninger, is\u00e6r n\u00e5r vi fors\u00f8ger at udvide databasens d\u00e6kning. <\/p>\n\n\n\n

Vi planl\u00e6gger at udvikle en ramme for behandling af naturligt sprog, der vil vurdere publikationer baseret p\u00e5 deres sandsynlighed for at dokumentere krydstale. En kurator kan s\u00e5 fokusere p\u00e5 h\u00f8jt rangerede publikationer,\" indr\u00f8mmer de.<\/p>\n\n\n\n

Artiklernes effekt og ydeevne<\/strong><\/h2>\n\n\n\n

Vi kan analysere med Altmetric<\/a> data, at dette papir er p\u00e5 \u00f8verste del af alle metrikker i alle artikler finansieret af NIH i Dimensions. <\/strong><\/p>\n\n\n

\n
\"\"<\/a>
Kilde: https:\/\/badge.dimensions.ai\/details\/id\/pub.1052462103<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Brug kraften i infografik til ogs\u00e5 at booste din artikel. Pr\u00f8v Mind the Graph!<\/p>\n\n\n\n

<\/div>\n\n\n\n
\n
Pr\u00f8v Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

L\u00e6r af dem, der allerede har opdaget styrken ved infografik. Denne artikel har grafiske abstracts lavet med Mind the Graph. <\/p>","protected":false},"author":29,"featured_media":20046,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"\nXTALKDB: a database of signaling pathway crosstalk Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"This amazing article brings out statistics summarizing data in XTALKDB with an infographic explaining the distribution of the species in XTALKDB.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/da\/succes-case-xtalkdb-a-database-over-signalveje-crosstalk\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"XTALKDB: a database of signaling pathway crosstalk Paper Review - 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