{"id":6385,"date":"2016-10-27T19:04:10","date_gmt":"2016-10-27T21:04:10","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=6385"},"modified":"2022-10-18T08:10:45","modified_gmt":"2022-10-18T11:10:45","slug":"senescent-cells-heart-diseases","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/cs\/senescentni-bunky-nemoci-srdce\/","title":{"rendered":"Senescentn\u00ed bu\u0148ky mohou m\u00edt vliv na srde\u010dn\u00ed choroby"},"content":{"rendered":"<p>Senescentn\u00ed bu\u0148ky jsou zn\u00e1m\u00e9 t\u00edm, \u017ee zp\u016fsobuj\u00ed st\u00e1rnut\u00ed na\u0161eho t\u011bla. Je to p\u0159irozen\u00fd b\u011bh v\u011bc\u00ed, tak\u017ee se tomu nelze divit. Proto\u017ee je v\u0161ak v\u0161e v na\u0161em organismu propojeno, zd\u00e1 se, \u017ee senescentn\u00ed bu\u0148ky mohou ovliv\u0148ovat mnohem v\u00edce, ne\u017e jsme si dosud mysleli. Vlastn\u011b mohou m\u00edt v\u011bt\u0161\u00ed pod\u00edl na vzniku n\u011bkter\u00fdch onemocn\u011bn\u00ed.<\/p>\n<blockquote><p>\"Hromad\u011bn\u00ed senescentn\u00edch bun\u011bk v na\u0161em t\u011ble m\u00e1 z\u00e1sadn\u00ed vliv na d\u00e9lku na\u0161eho \u017eivota - jak ukazuj\u00ed studie na my\u0161\u00edch.\" <a href=\"http:\/\/www.sciencemag.org\/news\/2016\/02\/suicide-aging-cells-prolongs-life-span-mice\">\u010casopis Science<\/a><\/p><\/blockquote>\n<p><a href=\"https:\/\/blog.mindthegraph.com\/writing-boring-paper\/\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-6379\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2016\/10\/output_fq1qro.gif\" alt=\"Senescentn\u00ed bu\u0148ky mohou m\u00edt vliv na srde\u010dn\u00ed choroby\" width=\"520\" height=\"390\" \/><\/a><\/p>\n<p>Dobr\u00e9 je, \u017ee se senescentn\u00ed bu\u0148ky p\u0159estanou mno\u017eit, a zabr\u00e1n\u00ed tak vzniku rakoviny z bun\u011bk, kter\u00e9 nejsou dostate\u010dn\u011b zdrav\u00e9, aby se mohly mno\u017eit. Nicm\u00e9n\u011b st\u00e1rnouc\u00ed bu\u0148ky se v na\u0161em t\u011ble st\u00e1le nach\u00e1zej\u00ed a dlouho v n\u011bm p\u0159etrv\u00e1vaj\u00ed.<\/p>\n<p>Tato skute\u010dnost je nesm\u00edrn\u011b d\u016fle\u017eit\u00e1, pokud se jedn\u00e1 o hromad\u011bn\u00ed bun\u011bk a dal\u0161\u00edch l\u00e1tek, kter\u00e9 mohou ovliv\u0148ovat na\u0161e t\u011blesn\u00e9 syst\u00e9my. Ned\u00e1vn\u00e9 studie t\u00fdkaj\u00edc\u00ed se kardiovaskul\u00e1rn\u00edch onemocn\u011bn\u00ed toti\u017e pouk\u00e1zaly na to, \u017ee senescentn\u00ed bu\u0148ky mohou p\u0159isp\u00edvat k rozvoji ateroskler\u00f3zy. P\u0159esn\u011bji \u0159e\u010deno, v\u011bdci se sna\u017e\u00ed pochopit, jakou roli hraj\u00ed senescentn\u00ed bu\u0148ky p\u0159i tvorb\u011b plaku b\u011bhem rozvoje ateroskler\u00f3zy.<\/p>\n<blockquote><p>\"Plaky se mohou st\u00e1t smrteln\u00fdmi, pokud prasknou a vytvo\u0159\u00ed krevn\u00ed sra\u017eeniny, kter\u00e9 mohou ucpat tepny a v\u00e9st k infarktu nebo mrtvici. Van Deursen a jeho kolegov\u00e9 zjistili, \u017ee u my\u0161\u00ed, u nich\u017e byly odstran\u011bny senescentn\u00ed bu\u0148ky, m\u011bly plaky siln\u011bj\u0161\u00ed ochrann\u00e9 obaly, a proto byla men\u0161\u00ed pravd\u011bpodobnost, \u017ee se zlom\u00ed.\" <a href=\"http:\/\/www.sciencemag.org\/news\/2016\/10\/are-old-cells-breaking-our-hearts\">\u010casopis Science<\/a><\/p><\/blockquote>\n<p><a href=\"https:\/\/blog.mindthegraph.com\/writing-boring-paper\/\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-6380\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2016\/10\/output_mqnorr.gif\" alt=\"Senescentn\u00ed bu\u0148ky mohou m\u00edt vliv na srde\u010dn\u00ed choroby\" width=\"573\" height=\"430\" \/><\/a><\/p>\n<p>Je\u0161t\u011b je t\u0159eba prov\u00e9st nov\u00e9 testy, ne\u017e bude mo\u017en\u00e9 p\u0159edpokl\u00e1dat skute\u010dnou roli st\u00e1rnouc\u00edch bun\u011bk p\u0159i kardiovaskul\u00e1rn\u00edch onemocn\u011bn\u00edch. Zd\u00e1 se v\u0161ak, \u017ee v\u011bdci jsou nov\u00fdm pohledem na ateroskler\u00f3zu velmi nad\u0161eni. \u010c\u00edm v\u00edce rozum\u00edme faktor\u016fm, kter\u00e9 se na vzniku ur\u010dit\u00e9ho onemocn\u011bn\u00ed pod\u00edlej\u00ed, t\u00edm snadn\u011bji lze do v\u00fdvoje onemocn\u011bn\u00ed zas\u00e1hnout a regresi prov\u00e9st.<\/p>\n<p>Pokud maj\u00ed v\u011bdci pravdu, mohli bychom p\u0159i prodlu\u017eov\u00e1n\u00ed d\u00e9lky \u017eivota hledat alternativn\u00ed zp\u016fsoby l\u00e9\u010dby nemoc\u00ed.<\/p>\n<p><a href=\"https:\/\/blog.mindthegraph.com\/writing-boring-paper\/\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-5831\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2016\/06\/untitled-creation63724.png\" alt=\"Senescentn\u00ed bu\u0148ky mohou m\u00edt vliv na srde\u010dn\u00ed choroby\" width=\"350\" height=\"140\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/06\/untitled-creation63724.png 1500w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/06\/untitled-creation63724-300x120.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/06\/untitled-creation63724-1024x410.png 1024w\" sizes=\"(max-width: 350px) 100vw, 350px\" \/><\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Senescentn\u00ed bu\u0148ky jsou zn\u00e1m\u00e9 t\u00edm, \u017ee zp\u016fsobuj\u00ed st\u00e1rnut\u00ed na\u0161eho t\u011bla. Je to p\u0159irozen\u00fd b\u011bh v\u011bc\u00ed, tak\u017ee se tomu nelze divit. Proto\u017ee je v\u0161ak v\u0161e v na\u0161em organismu propojeno, zd\u00e1 se, \u017ee senescentn\u00ed bu\u0148ky mohou ovliv\u0148ovat mnohem v\u00edce, ne\u017e jsme si dosud mysleli. Ve skute\u010dnosti mohou m\u00edt v\u011bt\u0161\u00ed pod\u00edl na vzniku n\u011bkter\u00fdch [...]<\/p>","protected":false},"author":11,"featured_media":6384,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[959,28],"tags":[554,250],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Senescent cells could be influencing heart diseases - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Aging is the natural course of things. 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