{"id":16662,"date":"2022-09-22T19:23:00","date_gmt":"2022-09-22T22:23:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16662"},"modified":"2023-03-17T14:46:01","modified_gmt":"2023-03-17T17:46:01","slug":"success-case-nmda-receptor-adjusted-co-administration-of-ecstasy-and-cannabinoid-receptor-1-agonist","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/cs\/uspesnost-pripad-nmda-receptoru-adjustovaneho-ko-podavani-ekstazy-a-kanabinoidniho-receptoru-1-agonisty\/","title":{"rendered":"NMDA receptor upraven\u00fd sou\u010dasn\u00fdm pod\u00e1v\u00e1n\u00edm ext\u00e1ze a agonisty kanabinoidn\u00edho receptoru-1 v amygdale prost\u0159ednictv\u00edm stimulace dr\u00e1hy BDNF\/Trk-B\/CREB u dosp\u011bl\u00fdch samc\u016f potkan\u016f Paper Review"},"content":{"rendered":"<p>Grafick\u00e9 abstrakty se st\u00e1vaj\u00ed mezi akademiky velmi obl\u00edben\u00fdmi. To znamen\u00e1, \u017ee autor vytvo\u0159il jeden \u00fa\u017easn\u00fd n\u00e1vrh, kter\u00fd vysv\u011btluje celou pointu tohoto \u010dl\u00e1nku s p\u0159esn\u00fdmi obr\u00e1zky.<\/p>\n\n\n\n<p>Pod\u00edvejte se na kompletn\u00ed <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0361923016303756\" target=\"_blank\" rel=\"noreferrer noopener\">p\u016fvodn\u00ed \u010dl\u00e1nek<\/a>.<\/p>\n\n\n\n<h2><strong>Konzumace selektivn\u00edho agonisty CB-1, jako je ACPA, chr\u00e1n\u00ed neurony p\u0159ed toxicitou MDMA v amygdale.<\/strong><\/h2>\n\n\n\n<p>Ashabi a jeho kolegov\u00e9 (2017) v \u010dl\u00e1nku \"NMDA receptor upravuje sou\u010dasn\u00e9 pod\u00e1v\u00e1n\u00ed ext\u00e1ze a agonisty kanabinoidn\u00edho receptoru 1 v amygdale prost\u0159ednictv\u00edm stimulace dr\u00e1hy BDNF\/Trk-B\/CREB u dosp\u011bl\u00fdch samc\u016f potkan\u016f\" uvedli, \u017ee blok\u00e1da NMDA sni\u017euje rychlost vypalov\u00e1n\u00ed neuron\u016f a hladinu proteinu v\u00e1zaj\u00edc\u00edho tyrozinkin\u00e1zu B\/neurotrofick\u00fd faktor odvozen\u00fd od mozku\/element v\u00e1zaj\u00edc\u00ed se na CAMP u potkan\u016f, kter\u00fdm byl sou\u010dasn\u011b pod\u00e1n MDMA a agonista receptoru CB1. <\/p>\n\n\n\n<p>Glutam\u00e1tergn\u00ed syst\u00e9m reguluje ochrannou roli kombinace MDMA a ACPA prost\u0159ednictv\u00edm receptor\u016f TrK-B.<\/p>\n\n\n\n<h2><strong>Grafick\u00e9 abstrakty zalo\u017een\u00e9 na Mind the Graph<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"835\" height=\"305\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png\" alt=\"\" class=\"wp-image-20094\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png 835w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-300x110.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-768x281.png 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-18x7.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-100x37.png 100w\" sizes=\"(max-width: 835px) 100vw, 835px\" \/><figcaption class=\"wp-element-caption\"><em>Vyrobeno s&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<p>Aktivace receptor\u016f CB1 nebo indukce MDMA sn\u00ed\u017eila rychlost vypalov\u00e1n\u00ed neuron\u016f. Sou\u010dasn\u00e1 injekce t\u011bchto dvou l\u00e9\u010div zv\u00fd\u0161ila p\u0159e\u017e\u00edv\u00e1n\u00ed neuron\u00e1ln\u00edch bun\u011bk a tyto jevy byly zvr\u00e1ceny prost\u0159ednictv\u00edm antagonisty NMDA receptor\u016f. <\/p>\n\n\n\n<p>Ochrann\u00e1 role glutam\u00e1tergn\u00edch receptor\u016f m\u016f\u017ee pravd\u011bpodobn\u011b spo\u010d\u00edvat v aktivaci BDNF\/Trk-B drah. <\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"718\" height=\"512\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png\" alt=\"\" class=\"wp-image-20093\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png 718w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-300x214.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-18x12.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-100x71.png 100w\" sizes=\"(max-width: 718px) 100vw, 718px\" \/><figcaption class=\"wp-element-caption\"><em>Vyrobeno s&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<h2><strong>Dokumenty Dopad a v\u00fdkon<\/strong><\/h2>\n\n\n\n<p>Pokud zvol\u00edme jednoletou variantu porovn\u00e1n\u00ed metrik s ostatn\u00edmi \u010dl\u00e1nky\/recenzemi, kter\u00e9 byly ve stejn\u00e9m kalend\u00e1\u0159n\u00edm roce v dan\u00e9m \u010dasopise rovn\u011b\u017e publikov\u00e1ny, m\u016f\u017eeme si v\u0161imnout, \u017ee <strong>tento \u010dl\u00e1nek byl citov\u00e1n v\u00edce ne\u017e 47% z nich.<\/strong>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"377\" height=\"330\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png\" alt=\"\" class=\"wp-image-20096\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png 377w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-300x263.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-14x12.png 14w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-100x88.png 100w\" sizes=\"(max-width: 377px) 100vw, 377px\" \/><\/figure>\n\n\n\n<p>Vyu\u017eijte s\u00edlu infografiky tak\u00e9 k pos\u00edlen\u00ed sv\u00e9ho \u010dl\u00e1nku. Vyzkou\u0161ejte Mind the Graph!<\/p>","protected":false},"excerpt":{"rendered":"<p>U\u010dte se s t\u011bmi, kte\u0159\u00ed ji\u017e objevili s\u00edlu infografiky. Tento \u010dl\u00e1nek obsahuje grafick\u00e9 abstrakty vytvo\u0159en\u00e9 pomoc\u00ed Mind the Graph. <\/p>","protected":false},"author":29,"featured_media":20081,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NMDA receptor adjusted co-administration of ecstasy and cannabinoid receptor-1 agonist in the amygdala via stimulation of BDNF\/Trk-B\/CREB pathway in adult male rats Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Learn with the ones who already discovered the power of infographics. 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