{"id":16651,"date":"2022-09-12T18:50:00","date_gmt":"2022-09-12T21:50:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16651"},"modified":"2023-03-17T14:47:35","modified_gmt":"2023-03-17T17:47:35","slug":"success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/cs\/uspech-pripad-imunoterapeuticky-potencial-protizanetlivych-a-imunosupresivnich-vlastnosti-krotoxinu\/","title":{"rendered":"Imunoterapeutick\u00fd potenci\u00e1l krotoxinu: protiz\u00e1n\u011btliv\u00e9 a imunosupresivn\u00ed vlastnosti P\u0159ehled \u010dl\u00e1nk\u016f"},"content":{"rendered":"

Vysv\u011btlit protiz\u00e1n\u011btlivou modulaci krotoxinu bez p\u0159\u00edslu\u0161n\u00fdch obr\u00e1zk\u016f by mohlo b\u00fdt trochu obt\u00ed\u017en\u00e9, ale pr\u00e1v\u011b proto existuje Mind the Graph!<\/p>\n\n\n\n

P\u0159ehled v\u011bdeck\u00e9ho v\u00fdzkumu krotoxinu, jedu ch\u0159est\u00fd\u0161e obecn\u00e9ho<\/strong><\/h2>\n\n\n\n

Marco Sartim et al. (2018) v \u010dl\u00e1nku \"Immunotherapeutic potential of Crotoxin\" uv\u00e1d\u00ed, \u017ee za posledn\u00edch 80 let se krotoxin stal jedn\u00edm z nejzkouman\u011bj\u0161\u00edch izolovan\u00fdch toxin\u016f z had\u00edch jed\u016f. <\/p>\n\n\n\n

Krotoxin je hlavn\u00ed toxickou slo\u017ekou jedu jihoamerick\u00e9ho ch\u0159est\u00fd\u0161e Crotalus durissus terrificus. Studie uk\u00e1zaly, \u017ee imunomodula\u010dn\u00ed \u00fa\u010dinek C.d.t. je spojen s produkc\u00ed protiz\u00e1n\u011btliv\u00fdch medi\u00e1tor\u016f. <\/p>\n\n\n\n

Schopnost krotoxinu a jeho podjednotek modulovat imunitn\u00ed syst\u00e9m p\u0159inesla nov\u00e9 perspektivy jako potenci\u00e1ln\u00edch terapeutick\u00fdch l\u00e1tek.<\/p>\n\n\n\n

V\u00fdzkumn\u00edci p\u0159ezkoumali 161 \u010dl\u00e1nk\u016f.<\/strong><\/p>\n\n\n\n

Zkontrolujte p\u016fvodn\u00ed \u010dl\u00e1nek zde<\/a>.<\/p>\n\n\n\n

Grafick\u00e9 abstrakty zalo\u017een\u00e9 na Mind the Graph<\/strong><\/h2>\n\n\n\n
<\/div>\n\n\n
\n
\"\"<\/a>
Vyrobeno s Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Autor pou\u017eil platformu Mind the Graph k vytvo\u0159en\u00ed schematick\u00e9ho obr\u00e1zku cirkulace, tk\u00e1\u0148ov\u00fdch a bun\u011b\u010dn\u00fdch d\u011bj\u016f modulovan\u00fdch krotoxinem a jeho podjednotkami b\u011bhem z\u00e1n\u011btliv\u00e9ho podn\u011btu.<\/p>\n\n\n\n

<\/div>\n\n\n
\n
\"\"<\/a>
Vyrobeno s Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Autor tak\u00e9 podrobn\u011b popsal krevn\u00ed ob\u011bh, nav\u00e1d\u011bn\u00ed lymfocyt\u016f do lymfatick\u00fdch uzlin a bun\u011b\u010dn\u00e9 d\u011bje spojen\u00e9 s imunosupresivn\u00edmi \u00fa\u010dinky krotoxinu a jeho podjednotek.<\/p>\n\n\n\n

To je s\u00edla infografiky!<\/strong><\/p>\n\n\n\n

Z\u00e1v\u011bry autor\u016f z\u0159ejm\u011b upev\u0148uj\u00ed p\u0159edchoz\u00ed pr\u00e1ce v t\u00e9to oblasti: \"Crotoxin byl schopen potla\u010dit specifickou produkci protil\u00e1tek anti-HSA IgG1 a IgG2a u my\u0161\u00ed imunizovan\u00fdch HAS, co\u017e ukazuje na jeho schopnost modulovat reakce Th1 a Th2,\" tvrd\u00ed Sartim.<\/p>\n\n\n\n

Dokumenty Dopad a v\u00fdkon<\/strong><\/h2>\n\n\n\n

M\u016f\u017eeme analyzovat pomoc\u00ed Altmetric<\/a> \u00fadaje, \u017ee tento \u010dl\u00e1nek m\u011bl v\u00edce citac\u00ed ne\u017e 84%<\/strong><\/strong> dal\u0161\u00edch \u010dl\u00e1nk\u016f z \u010dasopisu Springer Nature.<\/strong><\/p>\n\n\n

\n
\"\"<\/a>
Zdroj: Crossref<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Vyu\u017eijte s\u00edlu infografiky k pos\u00edlen\u00ed a ovlivnit v\u00e1\u0161 \u010dl\u00e1nek<\/a> tak\u00e9. Vyzkou\u0161ejte Mind the Graph!<\/p>\n\n\n\n

\n
Vyzkou\u0161ejte Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

Vysv\u011btlit protiz\u00e1n\u011btlivou modulaci krotoxinu bez pat\u0159i\u010dn\u00fdch obr\u00e1zk\u016f by mohlo b\u00fdt trochu obt\u00ed\u017en\u00e9, ale Mind the Graph existuje!<\/p>","protected":false},"author":29,"featured_media":20047,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"\nImmunotherapeutic potential of Crotoxin: anti-inflammatory and immunosuppressive properties Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"It could be a little difficult to explain the crotoxin\u2019s anti-inflammatory modulation without the proper images, but Mind the Graph exists!\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/cs\/uspech-pripad-imunoterapeuticky-potencial-protizanetlivych-a-imunosupresivnich-vlastnosti-krotoxinu\/\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Immunotherapeutic potential of Crotoxin: anti-inflammatory and immunosuppressive properties Paper Review - Mind the Graph Blog\" \/>\n<meta property=\"og:description\" content=\"It could be a little difficult to explain the crotoxin\u2019s anti-inflammatory modulation without the proper images, but Mind the Graph exists!\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/cs\/uspech-pripad-imunoterapeuticky-potencial-protizanetlivych-a-imunosupresivnich-vlastnosti-krotoxinu\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2022-09-12T21:50:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-17T17:47:35+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_6.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1125\" \/>\n\t<meta property=\"og:image:height\" content=\"614\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Artur Zignani\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_6.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Artur Zignani\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Immunotherapeutic potential of Crotoxin: anti-inflammatory and immunosuppressive properties Paper Review - 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