{"id":16092,"date":"2022-07-22T14:22:56","date_gmt":"2022-07-22T17:22:56","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16092"},"modified":"2022-10-18T08:29:39","modified_gmt":"2022-10-18T11:29:39","slug":"covid-or-the-effect-of-vaccination","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/cs\/covid-nebo-ucinek-ockovani\/","title":{"rendered":"Je to COVID nebo \u00fa\u010dinek o\u010dkov\u00e1n\u00ed? Kardiovaskul\u00e1rn\u00ed n\u00e1hl\u00e9 p\u0159\u00edhody"},"content":{"rendered":"

Po p\u0159ekon\u00e1n\u00ed nejt\u011b\u017e\u0161\u00edch \u010das\u016f COVID 19 na\u0161lo lidstvo nad\u011bji v o\u010dkov\u00e1n\u00ed. V\u0161echny nov\u00e9 biotechnologick\u00e9 pokroky n\u00e1m umo\u017enily bojovat s t\u011b\u017ek\u00fdmi \u010dasy COVID. Up\u0159\u00edmn\u011b \u0159e\u010deno, \u010dasu bylo m\u00e9n\u011b a lid\u00e9 um\u00edrali. Lidstvo se sna\u017eilo nejen naj\u00edt p\u0159\u00ed\u010dinu, ale tak\u00e9 p\u0159e\u017e\u00edt! <\/p>\n\n\n\n

N\u00e1strojem boje proti pandemii se stal multidisciplin\u00e1rn\u00ed p\u0159\u00edstup, rychlej\u0161\u00ed legislativn\u00ed opat\u0159en\u00ed a podpora komunity. Pot\u0159eba vypo\u0159\u00e1dat se s \u010dasovou t\u00edsn\u00ed, kterou u n\u00e1s p\u0159edstavoval COVID, vedla k faktick\u00e9mu sledov\u00e1n\u00ed v\u00fdroby vakc\u00edn, ale tak\u00e9 ke snaze o rychlej\u0161\u00ed schvalov\u00e1n\u00ed bez zkoum\u00e1n\u00ed dlouhodob\u00fdch \u00fa\u010dink\u016f nov\u011b vyvinut\u00fdch molekul.<\/p>\n\n\n\n

V\u0161echny slo\u017eky se sna\u017eily omezit \u0161\u00ed\u0159en\u00ed nezn\u00e1m\u00e9 hrozby a vrstvy zdravotnick\u00fdch slu\u017eeb se rozpadaly! V t\u011bch chv\u00edl\u00edch byly navr\u017eeny a testov\u00e1ny molekuly vakc\u00edn. Samotn\u00e1 nemoc nebyla zcela zn\u00e1ma a dlouhodob\u00e9 \u00fa\u010dinky zn\u011bly jako \u010dern\u00e1 d\u00edra. V\u0161echny st\u00e1ty a vl\u00e1dy souhlasily s bezplatn\u00fdm o\u010dkov\u00e1n\u00edm, aby zachr\u00e1nily lidi, nicm\u00e9n\u011b z v\u011bdeck\u00e9ho hlediska se objevilo mnoho spekulac\u00ed o tom, jak\u00e9 v\u0161echny budou kr\u00e1tkodob\u00e9 a dlouhodob\u00e9 \u00fa\u010dinky snahy o o\u010dkov\u00e1n\u00ed proti COVID na jednotlivce.<\/p>\n\n\n\n

Po t\u0159ech letech od prvn\u00edho v\u00fdskytu nemoci za\u010dali v\u011bdci podrobn\u011b analyzovat data, aby zjistili korelace a trendy pomoc\u00ed r\u016fzn\u00fdch srovn\u00e1n\u00ed. T\u00edmto nov\u00fdm typem \u010dl\u00e1nk\u016f od Mind the Graph se sna\u017e\u00edme poskytnout pohled na nej\u010dten\u011bj\u0161\u00ed \u010dl\u00e1nky renomovan\u00fdch \u010dasopis\u016f za ur\u010dit\u00e9 obdob\u00ed. Na\u0161i odborn\u00edci \u010dl\u00e1nky projdou, p\u0159iprav\u00ed grafick\u00e9 zn\u00e1zorn\u011bn\u00ed a naserv\u00edruj\u00ed je tak, aby co nejl\u00e9pe pochopily na\u0161e n\u00e1zory. Nechceme, aby v\u00e1m unikly \u017e\u00e1dn\u00e9 dobr\u00e9 \u010dl\u00e1nky a technologick\u00e9 novinky, na kter\u00e9 m\u016f\u017eeme vrhnout sv\u011btlo.<\/p>\n\n\n\n

V\u00fdzkumn\u00fd \u010dl\u00e1nek, kter\u00fd p\u0159edstavujeme tento t\u00fdden, nese n\u00e1zev, \"Zv\u00fd\u0161en\u00fd v\u00fdskyt akutn\u00edch kardiovaskul\u00e1rn\u00edch p\u0159\u00edhod u populace mlad\u0161\u00ed 40 let v Izraeli b\u011bhem zav\u00e1d\u011bn\u00ed vakc\u00edny a t\u0159et\u00ed vlny COVID-19\"<\/a> a pojedn\u00e1v\u00e1 p\u0159edev\u0161\u00edm o srde\u010dn\u00edch p\u0159\u00edhod\u00e1ch zaznamenan\u00fdch v dob\u011b po o\u010dkov\u00e1n\u00ed vakc\u00ednou COVID a zp\u011btn\u011b je porovn\u00e1v\u00e1 se srde\u010dn\u00edmi p\u0159\u00edhodami po o\u010dkov\u00e1n\u00ed vakc\u00ednou COVID.<\/p>\n\n\n\n

Ne\u017e za\u010dneme nahl\u00ed\u017eet do metodiky a pozorov\u00e1n\u00ed \u010dl\u00e1nku, za\u010dn\u011bme z\u00e1kladn\u00edm pochopen\u00edm v\u011bdeck\u00e9ho procesu v\u00fdvoje vakc\u00edn.<\/p>\n\n\n\n

Co jsou to vakc\u00edny?<\/strong><\/strong><\/h2>\n\n\n\n

Podle slovn\u00edkov\u00e9 definice jsou vakc\u00edny mal\u00e9 imunogenn\u00ed \u010d\u00e1stice, suspenze oslaben\u00fdch, usmrcen\u00fdch nebo fragmentovan\u00fdch mikroorganism\u016f nebo toxin\u016f nebo jin\u00fd biologick\u00fd p\u0159\u00edpravek, nap\u0159. slo\u017een\u00fd z protil\u00e1tek, lymfocyt\u016f nebo poselsk\u00e9 RNA (mRNA), kter\u00fd se pod\u00e1v\u00e1 p\u0159edev\u0161\u00edm za \u00fa\u010delem prevence onemocn\u011bn\u00ed. Kdy\u017e se lidsk\u00e9 t\u011blo vystav\u00ed oslaben\u00fdm \u010d\u00e1stic\u00edm antigenu, maj\u00ed tendenci vyvolat imunologickou odpov\u011b\u010f hostitelsk\u00e9ho t\u011bla, ale ne nutn\u011b onemocn\u011bn\u00ed.<\/p>\n\n\n\n

Molekuly vakc\u00edny se podobaj\u00ed patogen\u016fm a vyvol\u00e1vaj\u00ed imunitn\u00ed odpov\u011b\u010f, kter\u00e1 aktivuje B-bu\u0148ky produkuj\u00edc\u00ed IGg a vede k vytvo\u0159en\u00ed pam\u011bti pro tvorbu protil\u00e1tek proti dan\u00e9 molekule. Tento mechanismus pom\u00e1h\u00e1 lidem z\u00edskat dlouhodobou - kr\u00e1tkodobou ochranu proti infekci. Vakc\u00edny COVID vyv\u00edjej\u00ed tak\u00e9 farmaceutick\u00e9 spole\u010dnosti, aby n\u00e1s ochr\u00e1nily p\u0159ed smrtelnou progn\u00f3zou onemocn\u011bn\u00ed a smrt\u00ed.<\/p>\n\n\n\n

Komplikace COVID<\/strong><\/strong><\/h2>\n\n\n\n

Virus SARS COVID 19 ve sv\u00e9 podstat\u011b ohro\u017euje lidskou existenci. Hlavn\u00ed \u010dl\u00e1nek m\u011bs\u00edce pojedn\u00e1v\u00e1 o r\u016fzn\u00fdch kardiack\u00fdch komplikac\u00edch zp\u016fsoben\u00fdch touto nemoc\u00ed v pr\u016fb\u011bhu infek\u010dn\u00edho cyklu a o jej\u00edch dlouhodob\u00fdch n\u00e1sledc\u00edch. Auto\u0159i, Christopher L.F., Eli Jaffe & Retsef Levi z Izraele, podali stru\u010dn\u00fd p\u0159ehled kardiovaskul\u00e1rn\u00edch komplikac\u00ed zp\u016fsoben\u00fdch COVIDem.<\/p>\n\n\n\n

Jako \u010dast\u00e9 ne\u017e\u00e1douc\u00ed \u00fa\u010dinky p\u0159\u00edpravku COVID uv\u00e1d\u011bj\u00ed sr\u00e1\u017een\u00ed krve, akutn\u00ed koron\u00e1rn\u00ed syndrom, srde\u010dn\u00ed z\u00e1stavu a myokarditidu. Jsou hl\u00e1\u0161eny p\u0159\u00edpady posti\u017een\u00ed v\u00edce org\u00e1n\u016f p\u0159i l\u00e9\u010db\u011b p\u0159\u00edpravkem COVID a b\u011bhem p\u00e9\u010de po n\u011bm. U star\u0161\u00edch osob je obt\u00ed\u017en\u00e9 rozd\u011blit vliv onemocn\u011bn\u00ed a vliv v\u011bku a ji\u017e existuj\u00edc\u00edch klinick\u00fdch stav\u016f. Studie prezentovan\u00e1 autory tak jist\u011b vzbuzuje na\u0161i pozornost vzhledem k p\u0159eva\u017euj\u00edc\u00edm nal\u00e9hav\u00fdm zdravotn\u00edm stav\u016fm. <\/p>\n\n\n\n

Auto\u0159i si v\u0161imli, \u017ee mus\u00ed existovat ur\u010dit\u00e1 souvislost mezi zv\u00fd\u0161en\u00fdm po\u010dtem nal\u00e9hav\u00fdch p\u0159\u00edpad\u016f p\u0159ijat\u00fdch na n\u00e1rodn\u00ed t\u00eds\u0148ovou linku a \u010dasov\u00fdm rozvrhem o\u010dkov\u00e1n\u00ed. K pochopen\u00ed jemn\u00fdch hranic mezi dopadem po zaveden\u00ed vakc\u00edny COVID nebo dopadem o\u010dkov\u00e1n\u00ed, p\u0159\u00edpadn\u011b mezi v\u00fdsledky souvisej\u00edc\u00edmi s v\u011bkem a nal\u00e9hav\u00fdmi p\u0159\u00edpady, v\u0161ak bylo zapot\u0159eb\u00ed pe\u010dliv\u00e9ho a komplikovan\u00e9ho designu studie.<\/p>\n\n\n\n

V\u00fdzvy, kter\u00fdm \u010del\u00ed v\u00fdzkumn\u00ed pracovn\u00edci - n\u00e1vrh studie <\/strong><\/strong><\/h2>\n\n\n\n

V\u00fdzkumn\u00fd \u010dl\u00e1nek vych\u00e1z\u00ed z retrospektivn\u00edho popula\u010dn\u00edho pr\u016fzkumu z\u00e1chrann\u00fdch slu\u017eeb v Izraeli. C\u00edlem t\u00e9to studie je prozkoumat, jak mohou dodate\u010dn\u00e9 zdroje dat, nap\u0159\u00edklad od z\u00e1chrann\u00fdch zdravotnick\u00fdch slu\u017eeb (ZZS), doplnit syst\u00e9my dozoru nad o\u010dkov\u00e1n\u00edm, kter\u00e9 se samy hl\u00e1s\u00ed, p\u0159i zji\u0161\u0165ov\u00e1n\u00ed trend\u016f v oblasti ve\u0159ejn\u00e9ho zdrav\u00ed souvisej\u00edc\u00edch s COVID-19. <\/p>\n\n\n\n

Podle jejich vlastn\u00edch slov: \"S vyu\u017eit\u00edm unik\u00e1tn\u00edho souboru dat z izraelsk\u00e9 n\u00e1rodn\u00ed z\u00e1chrann\u00e9 slu\u017eby (EMS) z let 2019 a\u017e 2021 je c\u00edlem studie vyhodnotit souvislost mezi objemem vol\u00e1n\u00ed z\u00e1chrann\u00e9 slu\u017eby pro srde\u010dn\u00ed z\u00e1stavu a akutn\u00ed koron\u00e1rn\u00ed syndrom u populace 16-39 let s potenci\u00e1ln\u00edmi faktory v\u010detn\u011b infekce COVID-19 a m\u00edry o\u010dkov\u00e1n\u00ed.\" <\/p>\n\n\n\n

V\u00fdzkumn\u00edci pou\u017eili negativn\u00ed binomick\u00e9 regresn\u00ed modely k anal\u00fdze t\u00fddenn\u00edch po\u010dt\u016f t\u00eds\u0148ov\u00fdch vol\u00e1n\u00ed a pokusili se je spojit s 1. a 2. d\u00e1vkou vakc\u00edny COVID. V\u0161echny zdroje dat byly z n\u00e1rodn\u00edch center pro sb\u011br dat.<\/p>\n\n\n\n

<\/p>\n\n\n\n

\"\"<\/a>
Od:\u00a0Zv\u00fd\u0161en\u00fd v\u00fdskyt akutn\u00edch kardiovaskul\u00e1rn\u00edch p\u0159\u00edhod u populace mlad\u0161\u00ed 40 let v Izraeli b\u011bhem zav\u00e1d\u011bn\u00ed vakc\u00edny a t\u0159et\u00ed vlny COVID-19<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n\n

Pozorov\u00e1n\u00ed <\/strong><\/strong><\/h2>\n\n\n\n

Bylo zji\u0161t\u011bno, \u017ee byly v\u00fdznamn\u011b spojeny s m\u00edrou 1. a 2. d\u00e1vky vakc\u00edny podan\u00e9 t\u00e9to v\u011bkov\u00e9 skupin\u011b, ale nebyly spojeny s m\u00edrou infekce COVID-19. Auto\u0159i nenazna\u010duj\u00ed pouze v\u00fdzkumn\u00e1 pozorov\u00e1n\u00ed, ale nazna\u010duj\u00ed tak\u00e9 n\u011bkter\u00e9 politick\u00e9 d\u016fsledky. Navrhuj\u00ed vl\u00e1dn\u00ed intervence a zv\u00fd\u0161en\u00ed informovanosti pacient\u016f a l\u00e9ka\u0159\u016f. <\/p>\n\n\n\n

A\u010dkoli uv\u00e1d\u011bj\u00ed v\u0161echny kritick\u00e9 ukazatele, popsali tak\u00e9 omezen\u00ed studie, kter\u00e1 se op\u00edr\u00e1 o souhrnn\u00e9 \u00fadaje, je\u017e neobsahuj\u00ed konkr\u00e9tn\u00ed informace o posti\u017een\u00fdch pacientech, v\u010detn\u011b v\u00fdsledk\u016f hospitalizace, z\u00e1kladn\u00edch komorbidit a tak\u00e9 o\u010dkov\u00e1n\u00ed a pozitivity COVID-19.<\/p>\n\n\n\n

Mind the Graph <\/strong>oslavuje autory za jejich skv\u011blou pr\u00e1ci a p\u0159\u00ednos v\u011bdeck\u00e9 komunit\u011b. Pod\u011blte se o svou \u00fa\u017easnou pr\u00e1ci a my po\u017e\u00e1d\u00e1me n\u00e1\u0161 t\u00fdm, aby va\u0161i \u00fa\u017easnou pr\u00e1ci vyzdvihl grafick\u00fdm abstraktem! Poj\u010fme d\u011blat v\u011bdu. <\/p>\n\n\n\n

<\/p>\n\n\n\n

<\/div>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

\u010cl\u00e1nek pojedn\u00e1v\u00e1 o r\u016fzn\u00fdch srde\u010dn\u00edch komplikac\u00edch zp\u016fsoben\u00fdch COVID-19 b\u011bhem infek\u010dn\u00edho cyklu a o jeho dlouhodob\u00fdch \u00fa\u010dinc\u00edch. <\/p>","protected":false},"author":4,"featured_media":16097,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[419,956],"tags":[870,96,554,964],"yoast_head":"\nIs it COVID or the effect of vaccination? Cardiovascular emergencies<\/title>\n<meta name=\"description\" content=\"The featured article talks about various cardia complications caused by COVID-19 during its infection cycle and its long-term effects.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/cs\/covid-nebo-ucinek-ockovani\/\" \/>\n<meta property=\"og:locale\" content=\"cs_CZ\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Is it COVID or the effect of vaccination? 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He has a Ph.D. and solid scientific background in Psychopharmacology and experience as a Guest Researcher at the Max Planck Institute of Psychiatry (Germany) and Researcher in D'Or Institute for Research and Education (IDOR, Brazil). Fabricio holds over 2500 citations in Google Scholar. He has 10 years of experience in small innovative businesses, with relevant experience in product design and innovation management. 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