{"id":15202,"date":"2021-10-29T13:59:11","date_gmt":"2021-10-29T15:59:11","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=15202"},"modified":"2023-01-05T13:07:06","modified_gmt":"2023-01-05T16:07:06","slug":"mind-the-graph-and-3d-protein-imaging-2","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/cs\/mind-the-graph-and-3d-protein-imaging-2\/","title":{"rendered":"Mind the Graph a 3D zobrazov\u00e1n\u00ed protein\u016f"},"content":{"rendered":"

Zkou\u0161eli jste n\u011bkdy vytvo\u0159it molekul\u00e1rn\u00ed ilustraci pomoc\u00ed klasick\u00fdch molekul\u00e1rn\u00edch prohl\u00ed\u017ee\u010d\u016f? Pokud je odpov\u011b\u010f ano, pak u\u017e zn\u00e1te ten probl\u00e9m. <\/p>\n\n\n\n

Mus\u00edte si naj\u00edt bezplatnou verzi, kter\u00e1 v\u00e1m neshod\u00ed po\u010d\u00edta\u010d, a str\u00e1vit hodiny hled\u00e1n\u00edm zp\u016fsobu fungov\u00e1n\u00ed, p\u0159\u00edpadn\u011b i k\u00f3dov\u00e1n\u00edm. Bojovat s programy, kter\u00e9 jsou slo\u017eit\u00e9, neintuitivn\u00ed a \u010dasto vy\u017eaduj\u00ed licenci.<\/p>\n\n\n\n

Existuje \u0159e\u0161en\u00ed, kter\u00e9 se naz\u00fdv\u00e1 Protein Imager<\/a>!<\/p>\n\n\n\n

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Vytv\u00e1\u0159ejte efektivn\u00ed v\u011bdeck\u00e9 postavy b\u011bhem n\u011bkolika minut<\/a><\/div>\n<\/div>\n\n\n\n

O n\u00e1stroji Protein Imager<\/strong><\/h2>\n\n\n\n

Protein Imager<\/a> je bezplatn\u00fd webov\u00fd prohl\u00ed\u017ee\u010d molekul, kter\u00fd umo\u017e\u0148uje vytv\u00e1\u0159et molekul\u00e1rn\u00ed ilustrace na n\u011bkolik kliknut\u00ed. Byl vyvinut v\u011bdci z 3D studio pro zobrazov\u00e1n\u00ed protein\u016f<\/a> s c\u00edlem zefektivnit ilustraci b\u00edlkovin.<\/p>\n\n\n\n

Pro\u010d Protein Imager?<\/strong><\/h2>\n\n\n\n

Protein Imager se od ostatn\u00edch molekul\u00e1rn\u00edch prohl\u00ed\u017ee\u010d\u016f li\u0161\u00ed svou jednoduchost\u00ed a p\u0159\u00edstupnost\u00ed. Pro p\u0159\u00edstup ke v\u0161em funkc\u00edm programu Protein Imager se sta\u010d\u00ed p\u0159ihl\u00e1sit pomoc\u00ed e-mailu a p\u0159ipojen\u00ed k internetu.<\/p>\n\n\n\n

Protein Imager m\u00e1 u\u017eivatelsky p\u0159\u00edv\u011btiv\u00e9 rozhran\u00ed, kter\u00e9 umo\u017e\u0148uje p\u0159izp\u016fsoben\u00ed molekul\u00e1rn\u00ed ilustrace do v\u0161ech detail\u016f. U\u017eivatel si m\u016f\u017ee vybrat z r\u016fzn\u00fdch p\u0159ednastaven\u00fdch styl\u016f (kreslen\u00fd, realistick\u00fd, hrubozrnn\u00fd povrch) nebo si vizualizaci p\u0159izp\u016fsobit podle sv\u00fdch p\u0159edstav.<\/p>\n\n\n\n

\"\"<\/a>
P\u0159\u00edklady p\u0159ednastaven\u00fdch styl\u016f, kter\u00e9 lze pou\u017e\u00edt v aplikaci Protein Imager.<\/figcaption><\/figure>\n\n\n\n

Reprezentace molekul (povrch, kreslen\u00fd obr\u00e1zek, koule, ty\u010dinky atd.), re\u017eimy barven\u00ed, barvy pozad\u00ed, st\u00ednov\u00e1n\u00ed a okluze prost\u0159ed\u00ed jsou jen n\u011bkter\u00e9 z laditeln\u00fdch parametr\u016f, se kter\u00fdmi si u\u017eivatel\u00e9 mohou hr\u00e1t.<\/p>\n\n\n\n

\"\"\/<\/a><\/figure>\n\n\n\n

Odborn\u00edci maj\u00ed k dispozici tak\u00e9 n\u00e1stroje pro anal\u00fdzu dat, jako je superpozice struktur, prohl\u00ed\u017ee\u010d sekvenc\u00ed a v\u00fdb\u011bry.<\/p>\n\n\n\n

Nav\u00edc je kompletn\u011b online, co\u017e znamen\u00e1, \u017ee se nemus\u00edte instalovat lok\u00e1ln\u011b, \u0159e\u0161it zastaral\u00e9 verze ani probl\u00e9my s kompatibilitou s opera\u010dn\u00edmi syst\u00e9my. Ka\u017ed\u00e9 vykreslov\u00e1n\u00ed se op\u00edr\u00e1 o vyhrazen\u00fd server a doba vykreslov\u00e1n\u00ed je obvykle krat\u0161\u00ed ne\u017e 1 minuta v z\u00e1vislosti na slo\u017eitosti ilustrace.<\/p>\n\n\n\n

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Za\u010dn\u011bte tvo\u0159it na Mind the Graph hned te\u010f<\/a><\/div>\n<\/div>\n\n\n\n

Kdo pou\u017e\u00edv\u00e1 Protein Imager?<\/strong><\/h2>\n\n\n\n

Program Protein Imager je tak jednoduch\u00fd a intuitivn\u00ed, \u017ee jej m\u016f\u017ee vyu\u017e\u00edvat ka\u017ed\u00fd, od student\u016f a\u017e po zku\u0161en\u00e9 v\u011bdce. U\u017eivatel\u00e9 mohou popustit uzdu sv\u00e9 kreativit\u011b a vytv\u00e1\u0159et v\u011bdeck\u00e9 ilustrace pro r\u016fzn\u00e9 \u00fa\u010dely. <\/p>\n\n\n\n

Mnoz\u00ed v\u011bdci pou\u017eili n\u00e1stroj Protein Imager k ilustraci v\u00fdsledk\u016f sv\u00e9ho v\u00fdzkumu ve sv\u00fdch \u010dl\u00e1nc\u00edch nebo grafick\u00fdch abstraktech. <\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

Protein Imager pou\u017e\u00edvan\u00fd v\u011bdec Matteo Oliverio<\/a> k vytv\u00e1\u0159en\u00ed grafick\u00fdch abstrakt\u016f.<\/p>\n\n\n\n

Ti kreativn\u011bj\u0161\u00ed navrhuj\u00ed ob\u00e1lky \u010dasopis\u016f pomoc\u00ed aplikace Protein Imager. Ti, kte\u0159\u00ed se v\u011bnuj\u00ed v\u011bdeck\u00e9 komunikaci, pou\u017e\u00edvaj\u00ed Protein Imager k navrhov\u00e1n\u00ed poutav\u00fdch vizu\u00e1l\u016f pro sv\u00e9 p\u0159\u00edsp\u011bvky na soci\u00e1ln\u00edch s\u00edt\u00edch.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

Profesor Syma Khalid z Oxfordsk\u00e9 univerzity vytvo\u0159ila n\u00e1vrh ob\u00e1lky \u010dasopisu Structure, ro\u010dn\u00edk 29, \u010d\u00edslo 5, kv\u011bten 2021.<\/a>.<\/p>\n\n\n\n

V neposledn\u00ed \u0159ad\u011b m\u00e1 Protein Imager mo\u017enost exportovat molekuly jako objemov\u00e9 soubory (form\u00e1t VRML2), kter\u00e9 pou\u017e\u00edvaj\u00ed l\u00e9ka\u0159\u0161t\u00ed ilustr\u00e1to\u0159i v 3D grafick\u00fdch programech, jako jsou Blender, Cinema 4D, Maya.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

Obr\u00e1zek z portfolia studia v\u011bdeck\u00fdch ilustrac\u00ed BioSciVisuals.<\/a> K ilustraci molekul zahrnut\u00fdch do kone\u010dn\u00e9 grafick\u00e9 podoby plak\u00e1tu byl vedle profesion\u00e1ln\u00edch ilustra\u010dn\u00edch n\u00e1stroj\u016f pou\u017eit n\u00e1stroj Protein Imager.<\/p>\n\n\n\n

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Jste p\u0159ipraveni za\u010d\u00edt pracovat na Mind the Graph?<\/a><\/div>\n<\/div>\n\n\n\n

Nastartujte sv\u00e9 ilustrace<\/strong><\/h2>\n\n\n\n

Projdeme si z\u00e1kladn\u00ed kroky, kter\u00fdmi m\u016f\u017eete za\u010d\u00edt svou cestu za ilustrac\u00ed, ano?<\/p>\n\n\n\n

1 - Na\u010dten\u00ed molekul\u00e1rn\u00ed struktury<\/h3>\n\n\n\n

P\u0159ej\u00edt na Protein Imager<\/a> a nahr\u00e1t libovolnou molekul\u00e1rn\u00ed strukturu z po\u010d\u00edta\u010de nebo ji na\u010d\u00edst z biologick\u00fdch datab\u00e1z\u00ed, jako je Protein Data Bank nebo datab\u00e1ze Orientations of Proteins in Membranes (OPM).<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

2 - P\u0159izp\u016fsoben\u00ed<\/h3>\n\n\n\n

Prost\u0159ednictv\u00edm panelu struktury vpravo vyberte molekul\u00e1rn\u00ed reprezentaci a barevn\u00e1 sch\u00e9mata, v panelech vizualizace dola\u010fte st\u00ednov\u00e1n\u00ed, sv\u011btla, okoln\u00ed okluzi a vyberte p\u0159ednastaven\u00fd styl.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

3 - Z\u00edskejte obr\u00e1zek<\/h3>\n\n\n\n

Jakmile budete spokojeni s podobou sv\u00e9 stavby, po\u017e\u00e1dejte o vykreslen\u00ed.<\/p>\n\n\n\n

Za n\u011bkolik minut si budete moci st\u00e1hnout ilustraci ve vysok\u00e9 kvalit\u011b z panelu vykreslov\u00e1n\u00ed. V\u0161imn\u011bte si, \u017ee pro vy\u017e\u00e1d\u00e1n\u00ed vykreslen\u00ed se mus\u00edte zaregistrovat s platnou e-mailovou adresou.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

4 - Sd\u00edlejte ji se sv\u00fdmi spolupracovn\u00edky<\/h3>\n\n\n\n

A\u017e budete se svou prac\u00ed spokojeni, m\u016f\u017eete ji ulo\u017eit do u\u017eivatelsk\u00e9 slo\u017eky, kter\u00e1 pojme a\u017e 25 MB. Ke ka\u017ed\u00e9mu projektu m\u016f\u017eete z\u00edskat odkaz, kter\u00fd m\u016f\u017eete sd\u00edlet se spolupracovn\u00edky, aby v\u0161ichni m\u011bli stejn\u00fd p\u0159ehled.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n
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Za\u010dn\u011bte pou\u017e\u00edvat Mind The Graph pr\u00e1v\u011b te\u010f zdarma!<\/a><\/div>\n<\/div>\n\n\n\n

Mind the Graph a 3D zobrazov\u00e1n\u00ed protein\u016f<\/strong><\/h2>\n\n\n\n

3D Protein Imaging a Mind the Graph samoz\u0159ejm\u011b tvo\u0159\u00ed to nejlep\u0161\u00ed partnerstv\u00ed v\u016fbec! <\/p>\n\n\n\n

M\u016f\u017eete pou\u017e\u00edt sv\u016fj 3D obr\u00e1zek b\u00edlkoviny a nahr\u00e1t jej do sv\u00e9ho v\u00fdtvoru na Mind the Graph b\u011bhem sekundy. Chcete-li se nau\u010dit nahr\u00e1vat obr\u00e1zky, m\u016f\u017eete se pod\u00edvat na v\u00fdukov\u00e9 video. p\u0159\u00edmo zde<\/a>. <\/p>\n\n\n\n

Nebo p\u0159ejd\u011bte do sv\u00e9ho v\u00fdtvoru Mind the Graph, klikn\u011bte na polo\u017eku V\u00edce na<\/strong> v doln\u00ed \u010d\u00e1sti lev\u00e9ho menu a pak Nahr\u00e1t<\/strong>, vyberte obr\u00e1zek a po na\u010dten\u00ed jej p\u0159et\u00e1hn\u011bte na pracovn\u00ed plochu a je hotovo! <\/p>\n\n\n\n

Krom\u011b toho si m\u016f\u017eete vybrat jakoukoli ilustraci dostupnou v galerii Mind the Graph a pou\u017e\u00edt ji spole\u010dn\u011b s obr\u00e1zky sv\u00fdch protein\u016f. <\/p>\n\n\n\n

Galerie Mind the Graph obsahuje mnoho vizu\u00e1ln\u011b atraktivn\u00edch obr\u00e1zk\u016f pro v\u00e1\u0161 v\u00fdzkum, s v\u00edce ne\u017e 40 000 v\u011bdecky p\u0159esn\u00fdmi ilustracemi ve v\u00edce ne\u017e 80 popul\u00e1rn\u00edch oborech. Pokud pot\u0159ebujete ilustraci, najdete ji na Mind the Graph. <\/p>\n\n\n\n

Pokud jste p\u0159esto nena\u0161li to, co pot\u0159ebujete, nebo pokud pot\u0159ebujete velmi specifickou ilustraci, m\u016f\u017eete si vy\u017e\u00e1dat osobn\u00ed ilustraci a t\u00fdm ilustr\u00e1tor\u016f Mind the Graph ji pro v\u00e1s navrhne. V\u0161e, co mus\u00edte ud\u011blat, je vyplnit Mind the Graph \u017d\u00e1dost o ikonu<\/strong> formul\u00e1\u0159 uvnit\u0159 pracovn\u00edho prostoru se stru\u010dn\u00fdm vysv\u011btlen\u00edm a referen\u010dn\u00edm obr\u00e1zkem. Do t\u00fddne obdr\u017e\u00edte osobn\u00ed ilustraci. <\/p>\n\n\n\n

\u00da\u017easn\u00e9, \u017ee? <\/p>\n\n\n\n

Pod\u00edvejte se na video o tom, jak m\u016f\u017eete vytvo\u0159it v\u011bdeckou postavu pomoc\u00ed Mind the Graph a pou\u017e\u00edt extern\u00ed obr\u00e1zky z 3D Protein Imaging.<\/p>\n\n\n\n

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