{"id":16662,"date":"2022-09-22T19:23:00","date_gmt":"2022-09-22T22:23:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16662"},"modified":"2023-03-17T14:46:01","modified_gmt":"2023-03-17T17:46:01","slug":"success-case-nmda-receptor-adjusted-co-administration-of-ecstasy-and-cannabinoid-receptor-1-agonist","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/bg\/%d1%83%d1%81%d0%bf%d0%b5%d1%88%d0%b5%d0%bd-%d1%81%d0%bb%d1%83%d1%87%d0%b0%d0%b9-nmda-%d1%80%d0%b5%d1%86%d0%b5%d0%bf%d1%82%d0%be%d1%80%d0%bd%d0%be-%d0%b0%d0%b4%d0%b0%d0%bf%d1%82%d0%b8%d1%80%d0%b0%d0%bd\/","title":{"rendered":"NMDA \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440 \u043a\u043e\u0440\u0438\u0433\u0438\u0440\u0430 \u0441\u044a\u0432\u043c\u0435\u0441\u0442\u043d\u043e\u0442\u043e \u043f\u0440\u0438\u043b\u043e\u0436\u0435\u043d\u0438\u0435 \u043d\u0430 \u0435\u043a\u0441\u0442\u0430\u0437\u0438 \u0438 \u043a\u0430\u043d\u0430\u0431\u0438\u043d\u043e\u0438\u0434\u0435\u043d \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440-1 \u0430\u0433\u043e\u043d\u0438\u0441\u0442 \u0432 \u0430\u043c\u0438\u0433\u0434\u0430\u043b\u0430\u0442\u0430 \u0447\u0440\u0435\u0437 \u0441\u0442\u0438\u043c\u0443\u043b\u0438\u0440\u0430\u043d\u0435 \u043d\u0430 BDNF\/Trk-B\/CREB \u043f\u044a\u0442\u044f \u043f\u0440\u0438 \u0432\u044a\u0437\u0440\u0430\u0441\u0442\u043d\u0438 \u043c\u044a\u0436\u043a\u0438 \u043f\u043b\u044a\u0445\u043e\u0432\u0435 Paper Review"},"content":{"rendered":"<p>\u0413\u0440\u0430\u0444\u0438\u0447\u043d\u0438\u0442\u0435 \u0440\u0435\u0437\u044e\u043c\u0435\u0442\u0430 \u0441\u0442\u0430\u0432\u0430\u0442 \u043c\u043d\u043e\u0433\u043e \u043f\u043e\u043f\u0443\u043b\u044f\u0440\u043d\u0438 \u0441\u0440\u0435\u0434 \u0443\u0447\u0435\u043d\u0438\u0442\u0435. \u0422\u043e\u0432\u0430 \u043e\u0437\u043d\u0430\u0447\u0430\u0432\u0430, \u0447\u0435 \u0430\u0432\u0442\u043e\u0440\u044a\u0442 \u0435 \u0441\u044a\u0437\u0434\u0430\u043b \u0435\u0434\u0438\u043d \u043d\u0435\u0432\u0435\u0440\u043e\u044f\u0442\u0435\u043d \u0434\u0438\u0437\u0430\u0439\u043d, \u0437\u0430 \u0434\u0430 \u043e\u0431\u044f\u0441\u043d\u0438 \u0446\u0435\u043b\u0438\u044f \u0441\u043c\u0438\u0441\u044a\u043b \u043d\u0430 \u0442\u0430\u0437\u0438 \u0441\u0442\u0430\u0442\u0438\u044f \u0441 \u0442\u043e\u0447\u043d\u0438 \u0438\u0437\u043e\u0431\u0440\u0430\u0436\u0435\u043d\u0438\u044f.<\/p>\n\n\n\n<p>\u041f\u0440\u043e\u0432\u0435\u0440\u0435\u0442\u0435 \u043f\u044a\u043b\u043d\u0438\u044f <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0361923016303756\" target=\"_blank\" rel=\"noreferrer noopener\">\u043e\u0440\u0438\u0433\u0438\u043d\u0430\u043b\u043d\u0430 \u0441\u0442\u0430\u0442\u0438\u044f<\/a>.<\/p>\n\n\n\n<h2><strong>\u041a\u043e\u043d\u0441\u0443\u043c\u0430\u0446\u0438\u044f\u0442\u0430 \u043d\u0430 \u0441\u0435\u043b\u0435\u043a\u0442\u0438\u0432\u0435\u043d CB-1 \u0430\u0433\u043e\u043d\u0438\u0441\u0442 \u043a\u0430\u0442\u043e ACPA \u043f\u0440\u0435\u0434\u043f\u0430\u0437\u0432\u0430 \u043d\u0435\u0432\u0440\u043e\u043d\u0438\u0442\u0435 \u043e\u0442 \u0442\u043e\u043a\u0441\u0438\u0447\u043d\u043e\u0441\u0442\u0442\u0430 \u043d\u0430 MDMA \u0432 \u0430\u043c\u0438\u0433\u0434\u0430\u043b\u0430\u0442\u0430<\/strong><\/h2>\n\n\n\n<p>\u0412 \"NMDA \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440 \u0440\u0435\u0433\u0443\u043b\u0438\u0440\u0430 \u0441\u044a\u0432\u043c\u0435\u0441\u0442\u043d\u043e\u0442\u043e \u043f\u0440\u0438\u043b\u043e\u0436\u0435\u043d\u0438\u0435 \u043d\u0430 \u0435\u043a\u0441\u0442\u0430\u0437\u0438 \u0438 \u043a\u0430\u043d\u0430\u0431\u0438\u043d\u043e\u0438\u0434\u0435\u043d \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440-1 \u0430\u0433\u043e\u043d\u0438\u0441\u0442 \u0432 \u0430\u043c\u0438\u0433\u0434\u0430\u043b\u0430\u0442\u0430 \u0447\u0440\u0435\u0437 \u0441\u0442\u0438\u043c\u0443\u043b\u0438\u0440\u0430\u043d\u0435 \u043d\u0430 BDNF\/Trk-B\/CREB \u043f\u044a\u0442\u044f \u043f\u0440\u0438 \u0432\u044a\u0437\u0440\u0430\u0441\u0442\u043d\u0438 \u043c\u044a\u0436\u043a\u0438 \u043f\u043b\u044a\u0445\u043e\u0432\u0435\", Ashabi \u0438 \u043a\u043e\u043b\u0435\u0433\u0438 (2017) \u043e\u0442\u0431\u0435\u043b\u044f\u0437\u0432\u0430\u0442, \u0447\u0435 NMDA \u0431\u043b\u043e\u043a\u0430\u0434\u0430\u0442\u0430 \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430 \u0441\u043a\u043e\u0440\u043e\u0441\u0442\u0442\u0430 \u043d\u0430 \u043d\u0435\u0432\u0440\u043e\u043d\u043d\u0430\u0442\u0430 \u0441\u0442\u0440\u0435\u043b\u0431\u0430 \u0438 \u043d\u0438\u0432\u043e\u0442\u043e \u043d\u0430 \u0442\u0438\u0440\u043e\u0437\u0438\u043d-\u043a\u0438\u043d\u0430\u0437\u0430 \u0412\/\u043c\u043e\u0437\u044a\u0447\u0435\u043d \u043d\u0435\u0432\u0440\u043e\u0442\u0440\u043e\u0444\u0438\u0447\u0435\u043d \u0444\u0430\u043a\u0442\u043e\u0440\/\u0441\u0432\u044a\u0440\u0437\u0432\u0430\u0449 \u043f\u0440\u043e\u0442\u0435\u0438\u043d \u0441 \u0435\u043b\u0435\u043c\u0435\u043d\u0442 \u043d\u0430 \u043e\u0442\u0433\u043e\u0432\u043e\u0440 \u043d\u0430 \u043b\u0430\u0433\u0435\u0440\u0430 \u043f\u0440\u0438 \u043f\u043b\u044a\u0445\u043e\u0432\u0435, \u043d\u0430 \u043a\u043e\u0438\u0442\u043e \u0435 \u0438\u043d\u0436\u0435\u043a\u0442\u0438\u0440\u0430\u043d MDMA \u0438 CB1 \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0435\u043d \u0430\u0433\u043e\u043d\u0438\u0441\u0442. <\/p>\n\n\n\n<p>\u0413\u043b\u0443\u0442\u0430\u043c\u0430\u0442\u0435\u0440\u0433\u0438\u0447\u043d\u0430\u0442\u0430 \u0441\u0438\u0441\u0442\u0435\u043c\u0430 \u0440\u0435\u0433\u0443\u043b\u0438\u0440\u0430 \u0437\u0430\u0449\u0438\u0442\u043d\u0430\u0442\u0430 \u0440\u043e\u043b\u044f \u043d\u0430 \u043a\u043e\u043c\u0431\u0438\u043d\u0430\u0446\u0438\u044f\u0442\u0430 \u043e\u0442 MDMA \u0438 ACPA \u0447\u0440\u0435\u0437 TrK-B \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0438.<\/p>\n\n\n\n<h2><strong>\u0413\u0440\u0430\u0444\u0438\u0447\u043d\u0438 \u0440\u0435\u0437\u044e\u043c\u0435\u0442\u0430, \u0437\u0430\u0434\u0432\u0438\u0436\u0432\u0430\u043d\u0438 \u043e\u0442 Mind the Graph<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"835\" height=\"305\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png\" alt=\"\" class=\"wp-image-20094\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png 835w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-300x110.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-768x281.png 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-18x7.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-100x37.png 100w\" sizes=\"(max-width: 835px) 100vw, 835px\" \/><figcaption class=\"wp-element-caption\"><em>\u0418\u0437\u0440\u0430\u0431\u043e\u0442\u0435\u043d \u0441&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<p>\u0410\u043a\u0442\u0438\u0432\u0438\u0440\u0430\u043d\u0435\u0442\u043e \u043d\u0430 CB1 \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0438 \u0438\u043b\u0438 \u0438\u043d\u0434\u0443\u043a\u0446\u0438\u044f\u0442\u0430 \u043d\u0430 MDMA \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u0442 \u0441\u043a\u043e\u0440\u043e\u0441\u0442\u0442\u0430 \u043d\u0430 \u043d\u0435\u0432\u0440\u043e\u043d\u043d\u0438\u0442\u0435 \u0438\u0437\u0441\u0442\u0440\u0435\u043b\u0438. \u0415\u0434\u043d\u043e\u0432\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0442\u043e \u0438\u043d\u0436\u0435\u043a\u0442\u0438\u0440\u0430\u043d\u0435 \u043d\u0430 \u0442\u0435\u0437\u0438 \u0434\u0432\u0435 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430 \u0443\u0432\u0435\u043b\u0438\u0447\u0430\u0432\u0430 \u043f\u0440\u0435\u0436\u0438\u0432\u044f\u0435\u043c\u043e\u0441\u0442\u0442\u0430 \u043d\u0430 \u043d\u0435\u0432\u0440\u043e\u043d\u043d\u0438\u0442\u0435 \u043a\u043b\u0435\u0442\u043a\u0438 \u0438 \u0442\u0435\u0437\u0438 \u0441\u044a\u0431\u0438\u0442\u0438\u044f \u0441\u0435 \u043e\u0431\u0440\u044a\u0449\u0430\u0442 \u0447\u0440\u0435\u0437 \u0430\u043d\u0442\u0430\u0433\u043e\u043d\u0438\u0441\u0442 \u043d\u0430 NMDA \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0438\u0442\u0435. <\/p>\n\n\n\n<p>\u0412\u0435\u0440\u043e\u044f\u0442\u043d\u043e \u0437\u0430\u0449\u0438\u0442\u043d\u0430\u0442\u0430 \u0440\u043e\u043b\u044f \u043d\u0430 \u0433\u043b\u0443\u0442\u0430\u043c\u0430\u0442\u0435\u0440\u0433\u0438\u0447\u043d\u0438\u0442\u0435 \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0438 \u043c\u043e\u0436\u0435 \u0434\u0430 \u0441\u0435 \u0434\u044a\u043b\u0436\u0438 \u043d\u0430 \u0430\u043a\u0442\u0438\u0432\u0438\u0440\u0430\u043d\u0435\u0442\u043e \u043d\u0430 BDNF\/Trk-B \u043f\u044a\u0442\u0438\u0449\u0430\u0442\u0430. <\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"718\" height=\"512\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png\" alt=\"\" class=\"wp-image-20093\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png 718w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-300x214.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-18x12.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-100x71.png 100w\" sizes=\"(max-width: 718px) 100vw, 718px\" \/><figcaption class=\"wp-element-caption\"><em>\u0418\u0437\u0440\u0430\u0431\u043e\u0442\u0435\u043d \u0441&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<h2><strong>\u0414\u043e\u043a\u0443\u043c\u0435\u043d\u0442\u0438 \u0412\u044a\u0437\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435 \u0438 \u0435\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442<\/strong><\/h2>\n\n\n\n<p>\u0410\u043a\u043e \u0438\u0437\u0431\u0435\u0440\u0435\u043c \u0432\u0430\u0440\u0438\u0430\u043d\u0442 \u0437\u0430 \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435 \u043d\u0430 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0438\u0442\u0435 \u0437\u0430 \u0435\u0434\u043d\u0430 \u0433\u043e\u0434\u0438\u043d\u0430 \u0441\u043f\u0440\u044f\u043c\u043e \u0434\u0440\u0443\u0433\u0438 \u0441\u0442\u0430\u0442\u0438\u0438\/\u0440\u0435\u0446\u0435\u043d\u0437\u0438\u0438, \u043a\u043e\u0438\u0442\u043e \u0441\u0430 \u043f\u0443\u0431\u043b\u0438\u043a\u0443\u0432\u0430\u043d\u0438 \u043f\u0440\u0435\u0437 \u0441\u044a\u0449\u0430\u0442\u0430 \u043a\u0430\u043b\u0435\u043d\u0434\u0430\u0440\u043d\u0430 \u0433\u043e\u0434\u0438\u043d\u0430 \u0432 \u0442\u043e\u0432\u0430 \u0441\u043f\u0438\u0441\u0430\u043d\u0438\u0435, \u043c\u043e\u0436\u0435\u043c \u0434\u0430 \u0437\u0430\u0431\u0435\u043b\u0435\u0436\u0438\u043c, \u0447\u0435 <strong>\u0442\u0430\u0437\u0438 \u0441\u0442\u0430\u0442\u0438\u044f \u0435 \u0446\u0438\u0442\u0438\u0440\u0430\u043d\u0430 \u043f\u043e\u0432\u0435\u0447\u0435 \u043e\u0442 47% \u043e\u0442 \u0442\u044f\u0445<\/strong>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"377\" height=\"330\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png\" alt=\"\" class=\"wp-image-20096\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png 377w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-300x263.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-14x12.png 14w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-100x88.png 100w\" sizes=\"(max-width: 377px) 100vw, 377px\" \/><\/figure>\n\n\n\n<p>\u0418\u0437\u043f\u043e\u043b\u0437\u0432\u0430\u0439\u0442\u0435 \u0441\u0438\u043b\u0430\u0442\u0430 \u043d\u0430 \u0438\u043d\u0444\u043e\u0433\u0440\u0430\u0444\u0438\u043a\u0438\u0442\u0435, \u0437\u0430 \u0434\u0430 \u043f\u043e\u0434\u0441\u0438\u043b\u0438\u0442\u0435 \u0438 \u0441\u0442\u0430\u0442\u0438\u044f\u0442\u0430 \u0441\u0438. \u041e\u043f\u0438\u0442\u0430\u0439\u0442\u0435 Mind the Graph!<\/p>","protected":false},"excerpt":{"rendered":"<p>\u0423\u0447\u0435\u0442\u0435 \u0441\u0435 \u043e\u0442 \u0442\u0435\u0437\u0438, \u043a\u043e\u0438\u0442\u043e \u0432\u0435\u0447\u0435 \u0441\u0430 \u043e\u0442\u043a\u0440\u0438\u043b\u0438 \u0441\u0438\u043b\u0430\u0442\u0430 \u043d\u0430 \u0438\u043d\u0444\u043e\u0433\u0440\u0430\u0444\u0438\u043a\u0438\u0442\u0435. \u0422\u0430\u0437\u0438 \u0441\u0442\u0430\u0442\u0438\u044f \u0441\u044a\u0434\u044a\u0440\u0436\u0430 \u0433\u0440\u0430\u0444\u0438\u0447\u043d\u0438 \u0440\u0435\u0437\u044e\u043c\u0435\u0442\u0430, \u043d\u0430\u043f\u0440\u0430\u0432\u0435\u043d\u0438 \u0441 Mind the Graph. <\/p>","protected":false},"author":29,"featured_media":20081,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NMDA receptor adjusted co-administration of ecstasy and cannabinoid receptor-1 agonist in the amygdala via stimulation of BDNF\/Trk-B\/CREB pathway in adult male rats Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Learn with the ones who already discovered the power of infographics. 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